Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 3/20 | 0.39 |
| ▸ | FNTB | P49356 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1557481 | 0.87 | PPARG (0.41) | POLBFNTAFNTBLMNAMAPT | |
| SCHEMBL528543 | 0.83 | LMNA (0.39) | POLBLMNAKDM4EATMTRPA1 | |
| SCHEMBL528542 | 0.83 | LMNA (0.39) | POLBLMNAKDM4EATMTRPA1 | |
| SCHEMBL33626 | 0.81 | LMNA (0.42) | FNTAFNTBLMNASLC15A2MAPT | |
| SCHEMBL435540 | 0.81 | LMNA (0.42) | FNTAFNTBLMNASLC15A2MAPT | |
| SCHEMBL28772870 | 0.81 | — | — | |
| SCHEMBL17499861 | 0.79 | PPARG (0.41) | FNTAFNTBLMNASLC15A2MAPT | |
| SCHEMBL17499944 | 0.79 | PPARG (0.41) | FNTAFNTBLMNASLC15A2MAPT | |
| SCHEMBL11507795 | 0.78 | POLB (0.35) | POLBLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL11511188 | 0.78 | EP300 (0.37) | POLBLMNAMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10166527-B2 | Surface modification of porous base supports | MERCK PATENT GMBH (DE) | 2019-01-01 | — | — | US | claimed |
| EP-2310104-B1 | MIXED GRAFT POLYMERS FOR ION EXCHANGE CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2017-10-18 | — | — | EP | claimed |
| EP-2152405-B2 | GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2017-04-05 | — | — | EP | claimed |
| US-20150298097-A1 | SURFACE MODIFICATION OF POROUS BASE SUPPORTS | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | claimed |
| EP-2914377-A1 | SURFACE MODIFICATION OF POROUS BASE SUPPORTS | Merck Patent GmbH (DE) | 2015-09-09 | — | — | EP | claimed |
| WO-2014067605-A1 | SURFACE MODIFICATION OF POROUS BASE SUPPORTS | MERCK PATENT GMBH (DE) | 2014-05-08 | — | — | WO | claimed |
| US-8673988-B2 | Graft copolymers for ion exchange chromatography | MERCK PATENT GMBH (DE) | 2014-03-18 | — | — | US | claimed |
| EP-2152405-B1 | GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2012-10-17 | — | — | EP | claimed |
| JP-2011529508-A | — | — | 2011-12-08 | — | — | JP | claimed |
| US-20110136925-A1 | GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-06-09 | — | — | US | claimed |
| EP-2310104-A1 | GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY | Merck Patent GmbH (DE) | 2011-04-20 | — | — | EP | claimed |
| WO-2010012358-A1 | GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2010-02-04 | — | — | WO | claimed |
| JP-6116287-A | — | — | None | — | — | JP | disclosed |
| JP-5097699-A | — | — | None | — | — | JP | disclosed |
| US-20250032398-A1 | HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF | ISP INVESTMENTS LLC (US) | 2025-01-30 | — | — | US | disclosed |
| US-11446356-B2 | Peptides and related compositions and methods | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-09-20 | — | — | US | disclosed |
| JP-H06116287-A | PROPENAMIDE DERIVATIVE, ITS POLYMER AND ITS USE | FUJI PHOTO FILM CO LTD | 1994-04-26 | — | — | JP | disclosed |
| JP-H0597699-A | CANCER METASTASIS INHIBITOR COMPOSED OF PROPENAMIDE DERIVATIVE POLYMER | FUJI PHOTO FILM CO LTD | 1993-04-20 | — | — | JP | disclosed |
| EP-0503301-A2 | Peptide derivatives and application thereof | FUJI PHOTO FILM CO., LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |
| JP-H00597699-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250032398-A1 | HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF | PCNA, ADSL, APH1B | POLB 216/4885FNTA 2726/4885FNTB 1330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.