Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17915422 | 0.77 | KDM4E (0.50) | KDM4ETDP1MAPK1L3MBTL1MAPT | |
| SCHEMBL17682959 | 0.75 | TDP1 (0.33) | KDM4ETDP1MAPK1L3MBTL1MAPT | |
| SCHEMBL3499851 | 0.72 | KDM4E (0.50) | KDM4ETDP1MAPK1L3MBTL1MAPT | |
| SCHEMBL18473301 | 0.72 | ALDH1A1 (0.38) | KDM4ETDP1MAPK1MAPTALDH1A1 | |
| SCHEMBL4071671 | 0.72 | ALDH1A1 (0.43) | KDM4EMAPK1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL21450773 | 0.70 | MGLL (0.40) | L3MBTL1HPGDSMN1; SMN2CA1CA2 | |
| SCHEMBL28402732 | 0.70 | KDM4E (0.48) | KDM4ETDP1MAPK1L3MBTL1MAPT | |
| SCHEMBL11793107 | 0.70 | KDM4E (0.48) | KDM4ETDP1MAPK1L3MBTL1MAPT | |
| SCHEMBL6563914 | 0.69 | ALDH1A1 (0.54) | KDM4ETDP1MAPK1L3MBTL1MAPT | |
| SCHEMBL19305695 | 0.69 | KDM4E (0.47) | KDM4ETDP1MAPK1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014025424-A2 | BORON-NITROGEN-CONTAINING ACENE COMPOUNDS AND THEIR PREPARATION | STATE OF OREGON ACTING BY & THROUGH THE STATE BOARD OF HIGHER EDUC. ON BEHALF OF THE UNIV. OF OREGON (US) | 2014-02-13 | — | — | WO | disclosed |