Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15502414 | 0.79 | POLB (0.41) | L3MBTL1POLBMEN1KMT2ACREBBP | |
| SCHEMBL18383143 | 0.76 | POLB (0.47) | L3MBTL1POLBMEN1KMT2ACREBBP | |
| SCHEMBL1520547 | 0.76 | POLB (0.47) | L3MBTL1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL16975409 | 0.75 | POLB (0.46) | L3MBTL1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL6970538 | 0.75 | MEN1 (0.49) | L3MBTL1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL16975408 | 0.74 | MAPK1 (0.46) | L3MBTL1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL6970534 | 0.73 | POLB (0.43) | L3MBTL1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL18130329 | 0.72 | VCAM1 (0.41) | L3MBTL1POLBMEN1KMT2ACREBBP | |
| SCHEMBL16523977 | 0.72 | POLB (0.42) | L3MBTL1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL20555350 | 0.71 | POLB (0.42) | L3MBTL1POLBMEN1KMT2ACREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104736533-B | Vegfr3 inhibitor | 癌症治疗合作研究中心有限公司 | 2016-12-07 | — | — | CN | disclosed |
| EP-2885291-A1 | VEGFR3 INHIBITORS | Cancer Therapeutics Crc Pty Limited (AU) | 2015-06-24 | — | — | EP | disclosed |
| WO-2014026243-A1 | VEGFR3 INHIBITORS | CANCER THERAPEUTICS CRC PTY LIMITED (AU) | 2014-02-20 | — | — | WO | disclosed |