Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970538 | 0.78 | MEN1 (0.49) | POLBL3MBTL1PKMALDH1A1MEN1 | |
| SCHEMBL16975468 | 0.76 | SMN1; SMN2 (0.41) | POLBL3MBTL1PKMALDH1A1MEN1 | |
| SCHEMBL16523977 | 0.74 | POLB (0.42) | POLBL3MBTL1PKMALDH1A1MEN1 | |
| SCHEMBL15567232 | 0.73 | L3MBTL1 (0.51) | POLBL3MBTL1PKMALDH1A1MEN1 | |
| SCHEMBL21719655 | 0.73 | LMNA (0.44) | POLBL3MBTL1PKMALDH1A1MEN1 | |
| SCHEMBL26120909 | 0.73 | POLB (0.41) | POLBL3MBTL1PKMALDH1A1MEN1 | |
| SCHEMBL6161956 | 0.72 | ALDH1A1 (0.41) | POLBL3MBTL1PKMALDH1A1MEN1 | |
| SCHEMBL16975493 | 0.72 | CRHBP (0.41) | POLBL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL20353782 | 0.72 | POLB (0.40) | POLBL3MBTL1PKMALDH1A1MEN1 | |
| SCHEMBL26120935 | 0.72 | POLB (0.40) | POLBL3MBTL1PKMALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |