Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970538 | 0.76 | MEN1 (0.49) | POLBL3MBTL1PKMMEN1KMT2A | |
| SCHEMBL6970534 | 0.74 | POLB (0.43) | POLBL3MBTL1PKMMEN1KMT2A | |
| SCHEMBL21719655 | 0.72 | LMNA (0.44) | POLBL3MBTL1PKMMEN1KMT2A | |
| SCHEMBL26120909 | 0.72 | POLB (0.41) | POLBL3MBTL1PKMMEN1KMT2A | |
| SCHEMBL15567232 | 0.72 | L3MBTL1 (0.51) | POLBL3MBTL1PKMMEN1KMT2A | |
| SCHEMBL20353782 | 0.70 | POLB (0.40) | POLBL3MBTL1PKMMEN1KMT2A | |
| SCHEMBL26120935 | 0.70 | POLB (0.40) | POLBL3MBTL1PKMMEN1KMT2A | |
| SCHEMBL16975468 | 0.70 | SMN1; SMN2 (0.41) | POLBL3MBTL1PKMMEN1KMT2A | |
| SCHEMBL23275100 | 0.69 | PKM (0.40) | POLBL3MBTL1PKMMEN1KMT2A | |
| SCHEMBL20555350 | 0.69 | POLB (0.42) | POLBL3MBTL1PKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015025197-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF | JUBILANT BIOSYS LIMITED (IN) | 2015-02-26 | — | — | WO | disclosed |