Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 5/20 | 0.41 |
| ▸ | CHUK | O15111 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10258859 | 1.00 | IKBKB (0.41) | IKBKBCHUKPIM1PIM2FEN1 | |
| Hydrochloric Acid SCHEMBL15566496 | 0.99 | IKBKB (0.41) | IKBKBCHUKPIM1PIM2FEN1 | |
| Hydrochloric Acid SCHEMBL15566494 | 0.99 | IKBKB (0.41) | IKBKBCHUKPIM1PIM2FEN1 | |
| SCHEMBL15605503 | 0.94 | IRAK4 (0.41) | IKBKBCHUKIRAK4ROCK2ROCK1 | |
| SCHEMBL10257966 | 0.94 | IRAK4 (0.41) | IKBKBCHUKIRAK4ROCK2ROCK1 | |
| SCHEMBL2419230 | 0.89 | MCHR1 (0.46) | IKBKBMCHR1 | |
| SCHEMBL27102256 | 0.88 | MCHR1 (0.47) | IKBKBMCHR1 | |
| SCHEMBL6015806 | 0.87 | IKBKB (0.41) | IKBKBCHUKPIM1PIM2MCHR1 | |
| SCHEMBL2416840 | 0.86 | MCHR1 (0.40) | IKBKBCHUKFEN1MCHR1 | |
| Hydrochloric Acid SCHEMBL16205102 | 0.86 | IKBKB (0.45) | IKBKBCHUKPIM1PIM2FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240065302-A1 | SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF | FIRMENICH INCORPORATED | 2024-02-29 | — | — | US | disclosed |
| CN-104603132-B | Sweet taste modifier | 弗门尼舍公司 | 2020-02-21 | — | — | CN | disclosed |
| US-20180086751-A1 | SWEETENER COMPOSITION | SENOMYX, INC. | 2018-03-29 | — | — | US | disclosed |
| US-20170354175-A1 | SWEETENER COMPOSITION | SENOMYX, INC. | 2017-12-14 | — | — | US | disclosed |
| EP-2880031-A1 | SWEET FLAVOR MODIFIER | Senomyx, Inc. (US) | 2015-06-10 | — | — | EP | disclosed |
| WO-2014025706-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2014-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086751-A1 | SWEETENER COMPOSITION | TAS2R50, TAS1R2, TAS2R10 | IKBKB 4600/4885CHUK 4475/4885PIM1 2936/4885 |
| US-20170354175-A1 | SWEETENER COMPOSITION | TAS1R2, TAS1R1, TAS2R50 | IKBKB 4663/4885CHUK 4544/4885PIM1 3516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.