Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15567283 | 0.74 | NPC1 (0.38) | NPC1RAB9ANPSR1MAOBALDH1A1 | |
| SCHEMBL22279199 | 0.73 | NPC1 (0.62) | NPC1RAB9ANPSR1MAOBALDH1A1 | |
| SCHEMBL26633344 | 0.70 | NPC1 (0.57) | NPC1RAB9ANPSR1MAOBALDH1A1 | |
| SCHEMBL28282010 | 0.69 | NPC1 (0.56) | NPC1RAB9ANPSR1MAOBALDH1A1 | |
| SCHEMBL29739399 | 0.69 | NPC1 (0.56) | NPC1RAB9ANPSR1MAOBALDH1A1 | |
| SCHEMBL3986269 | 0.69 | NPC1 (0.63) | NPC1RAB9ANPSR1MAOBALDH1A1 | |
| SCHEMBL1890797 | 0.69 | RAB9A (0.63) | NPC1RAB9ANPSR1ALDH1A1CYP1A2 | |
| SCHEMBL10356846 | 0.68 | RAB9A (0.81) | NPC1RAB9ANPSR1MAOBALDH1A1 | |
| SCHEMBL16907485 | 0.68 | NPSR1 (0.61) | NPC1RAB9ANPSR1MAOBALDH1A1 | |
| SCHEMBL29739599 | 0.68 | NPSR1 (0.61) | NPC1RAB9ANPSR1MAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9518045-B2 | Process for manufacturing benzoxazinones | BASF SE (DE) | 2016-12-13 | — | — | US | disclosed |
| US-9518045-B2 | Process for manufacturing benzoxazinones | BASF SE (DE) | 2016-12-13 | — | — | US | disclosed |
| US-9518045-B2 | Process for manufacturing benzoxazinones | BASF SE (DE) | 2016-12-13 | — | — | US | disclosed |
| US-9409894-B2 | Carbamates | BASF SE (DE) | 2016-08-09 | — | — | US | disclosed |
| US-9409894-B2 | Carbamates | BASF SE (DE) | 2016-08-09 | — | — | US | disclosed |
| US-9409894-B2 | Carbamates | BASF SE (DE) | 2016-08-09 | — | — | US | disclosed |
| EP-2885296-B1 | PROCESS FOR MANUFACTURING BENZOXAZINONES | BASF SE (DE) | 2016-06-29 | — | — | EP | disclosed |
| EP-2885296-B1 | PROCESS FOR MANUFACTURING BENZOXAZINONES | BASF SE (DE) | 2016-06-29 | — | — | EP | disclosed |
| US-9353070-B2 | Carbamat-benzoxazinones | BASF SE (DE) | 2016-05-31 | — | — | US | disclosed |
| US-9353070-B2 | Carbamat-benzoxazinones | BASF SE (DE) | 2016-05-31 | — | — | US | disclosed |
| US-20150218139-A1 | CARBAMATES | BASF SE (DE) | 2015-08-06 | — | — | US | disclosed |
| US-20150218140-A1 | PROCESS FOR MANUFACTURING BENZOXAZINONES | BASF SE (DE) | 2015-08-06 | — | — | US | disclosed |
| US-20150218140-A1 | PROCESS FOR MANUFACTURING BENZOXAZINONES | BASF SE (DE) | 2015-08-06 | — | — | US | disclosed |
| US-20150218140-A1 | PROCESS FOR MANUFACTURING BENZOXAZINONES | BASF SE (DE) | 2015-08-06 | — | — | US | disclosed |
| US-20150218139-A1 | CARBAMATES | BASF SE (DE) | 2015-08-06 | — | — | US | disclosed |
| US-20150218139-A1 | CARBAMATES | BASF SE (DE) | 2015-08-06 | — | — | US | disclosed |
| EP-2885296-A1 | PROCESS FOR MANUFACTURING BENZOXAZINONES | BASF SE (DE) | 2015-06-24 | — | — | EP | disclosed |
| EP-2885281-A1 | CARBAMAT-BENZOXAZINONES | BASF SE (DE) | 2015-06-24 | — | — | EP | disclosed |
| WO-2014026928-A1 | PROCESS FOR MANUFACTURING BENZOXAZINONES | BASF SE (DE) | 2014-02-20 | — | — | WO | disclosed |
| WO-2014026893-A1 | CARBAMAT-BENZOXAZINONES | BASF SE (DE) | 2014-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150218140-A1 | PROCESS FOR MANUFACTURING BENZOXAZINONES | CYP4X1, CYP3A5, CYP2B6 | NPC1 3213/4885RAB9A 2775/4885NPSR1 2226/4885 |
| US-20150218139-A1 | CARBAMATES | CYP4X1, CYP2B6, CBX7 | NPC1 2667/4885RAB9A 1962/4885NPSR1 1808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.