Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3986269 | 0.88 | NPC1 (0.63) | RAB9ANPC1NPSR1SMN1; SMN2HTT | |
| SCHEMBL26697273 | 0.86 | NPC1 (0.61) | RAB9ANPC1NPSR1SMN1; SMN2HTT | |
| SCHEMBL21319206 | 0.85 | RAB9A (0.60) | RAB9ANPC1NPSR1SMN1; SMN2POLB | |
| SCHEMBL29563219 | 0.85 | NPC1 (0.61) | RAB9ANPC1NPSR1SMN1; SMN2HTT | |
| SCHEMBL24382006 | 0.85 | NPC1 (0.61) | RAB9ANPC1NPSR1SMN1; SMN2HTT | |
| SCHEMBL23539851 | 0.85 | KMT2A (0.54) | RAB9ANPC1NPSR1POLBKMT2A | |
| SCHEMBL22279199 | 0.84 | NPC1 (0.62) | RAB9ANPC1NPSR1SMN1; SMN2HTT | |
| SCHEMBL5338241 | 0.84 | RAB9A (0.58) | RAB9ANPC1NPSR1SMN1; SMN2HTT | |
| SCHEMBL10356846 | 0.83 | RAB9A (0.81) | RAB9ANPC1NPSR1SMN1; SMN2KMT2A | |
| SCHEMBL5345691 | 0.82 | KMT2A (0.60) | RAB9ANPC1NPSR1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372981-B2 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-02-12 | — | — | US | disclosed |
| US-8372981-B2 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-02-12 | — | — | US | disclosed |
| US-7973160-B2 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-07-05 | — | — | US | disclosed |
| US-7973160-B2 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-07-05 | — | — | US | disclosed |
| US-7973160-B2 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-07-05 | — | — | US | disclosed |
| US-20110118470-A1 | NITROGEN-CONTAINING AROMATIC DERIVATIVES | FUNAHASHI YASUHIRO | 2011-05-19 | — | — | US | disclosed |
| US-20110118470-A1 | NITROGEN-CONTAINING AROMATIC DERIVATIVES | FUNAHASHI YASUHIRO | 2011-05-19 | — | — | US | disclosed |
| US-20100197911-A1 | Nitrogen-Containing Aromatic Derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-08-05 | — | — | US | disclosed |
| US-20100197911-A1 | Nitrogen-Containing Aromatic Derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-08-05 | — | — | US | disclosed |
| US-20100197911-A1 | Nitrogen-Containing Aromatic Derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-08-05 | — | — | US | disclosed |
| US-5371101-A | Fungicides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0567982-A1 | Azole compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1993-11-03 | — | — | EP | disclosed |
| US-5003106-A | Antiatherosclerotic ureas and thioureas | AMERICAN CYANAMID COMPANY (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0144853-B1 | SEMICARBAZIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |
| US-4725608-A | ANTIINFLAMMATORY, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-02-16 | — | — | US | disclosed |
| US-4623662-A | ANTICHOLESTEROL, ANTILIPEMIC | AMERICAN CYANAMID COMPANY (US) | 1986-11-18 | — | — | US | disclosed |
| EP-0144853-A2 | Semicarbazide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |
| US-4396621-A | ANALGESICS, ANTIIMFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1983-08-02 | — | — | US | disclosed |
| US-4320138-A | ANTIINFLAMMATORY AGENTS FOR ARTHRITIS, GOUT | CIBA-GEIGY CORPORATION (US) | 1982-03-16 | — | — | US | disclosed |
| US-4260779-A | ANALGESICS, ANTIINFLAMMATORY, DIURETICS | CIBA-GEIGY CORPORATION (US) | 1981-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197911-A1 | Nitrogen-Containing Aromatic Derivatives | GNG2, GCG, FRG1 | RAB9A 2404/4885NPC1 910/4885NPSR1 2897/4885 |
| US-20110118470-A1 | NITROGEN-CONTAINING AROMATIC DERIVATIVES | GNG2, GCG, FRG1 | RAB9A 2592/4885NPC1 798/4885NPSR1 2659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.