Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 7/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14115107 | 0.88 | GPR119 (0.52) | NPY2RGPR119KMT2AKDM4EPKM | |
| SCHEMBL239883 | 0.84 | NPY2R (0.65) | NPY2RGPR119KMT2AALDH1A1KDM4E | |
| SCHEMBL22491552 | 0.78 | MEN1 (0.60) | NPY2RGPR119KMT2AALDH1A1KDM4E | |
| SCHEMBL22773246 | 0.78 | MEN1 (0.60) | NPY2RGPR119KMT2AALDH1A1KDM4E | |
| SCHEMBL3655794 | 0.78 | NPY2R (0.58) | NPY2RGPR119KMT2AALDH1A1KDM4E | |
| SCHEMBL23212017 | 0.78 | NPY2R (0.50) | NPY2RGPR119ALDH1A1KDM4EPKM | |
| SCHEMBL30568007 | 0.78 | NPY2R (0.50) | NPY2RGPR119ALDH1A1KDM4EPKM | |
| SCHEMBL3659737 | 0.77 | GPR119 (0.61) | NPY2RGPR119KMT2AKDM4EPKM | |
| SCHEMBL16932529 | 0.76 | NPY2R (0.48) | NPY2RGPR119KMT2AALDH1A1KDM4E | |
| SCHEMBL15568941 | 0.76 | HRH1 (0.60) | KMT2AALDH1A1KDM4EPKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9505752-B2 | Piperidine amide derivatives as HIV attachment inhibitors | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2016-11-29 | — | — | US | disclosed |
| US-9505752-B2 | Piperidine amide derivatives as HIV attachment inhibitors | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2016-11-29 | — | — | US | disclosed |
| US-9505752-B2 | Piperidine amide derivatives as HIV attachment inhibitors | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2016-11-29 | — | — | US | disclosed |
| EP-2895471-B1 | PIPERIDINE AMIDE DERIVATIVES AS HIV ATTACHMENT INHIBITORS | VIIV HEALTHCARE UK NO 5 LTD (GB) | 2016-11-23 | — | — | EP | disclosed |
| EP-2895471-B1 | PIPERIDINE AMIDE DERIVATIVES AS HIV ATTACHMENT INHIBITORS | VIIV HEALTHCARE UK NO 5 LTD (GB) | 2016-11-23 | — | — | EP | disclosed |
| US-20150210684-A1 | PIPERIDINE AMIDE DERIVATIVES AS HIV ATTACHMENT INHIBITORS | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2015-07-30 | — | — | US | disclosed |
| US-20150210684-A1 | PIPERIDINE AMIDE DERIVATIVES AS HIV ATTACHMENT INHIBITORS | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2015-07-30 | — | — | US | disclosed |
| US-20150210684-A1 | PIPERIDINE AMIDE DERIVATIVES AS HIV ATTACHMENT INHIBITORS | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2015-07-30 | — | — | US | disclosed |
| EP-2895471-A1 | PIPERIDINE AMIDE DERIVATIVES AS HIV ATTACHMENT INHIBITORS | Bristol-Myers Squibb Company (US) | 2015-07-22 | — | — | EP | disclosed |
| WO-2014025854-A1 | PIPERIDINE AMIDE DERIVATIVES AS HIV ATTACHMENT INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210684-A1 | PIPERIDINE AMIDE DERIVATIVES AS HIV ATTACHMENT INHIBITORS | CD4, HDAC5, ITGA5 | NPY2R 4809/4885GPR119 3381/4885KMT2A 1503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.