SCHEMBL239883

SCHEMBL239883

CC(C)(C)OC(=O)N1CCC(C(O)(c2ccccc2)c2ccccc2)CC1

nearest known ligand 0.65

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPY2R P49146 9/20 0.65
ALDH1A1 P00352 2/20 0.62
GPR119 Q8TDV5 1/20 0.60
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
KDM4E B2RXH2 2/20 0.55
MAPT P10636 1/20 0.55
PKM P14618 1/20 0.54
LMNA P02545 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3655794 0.93 NPY2R (0.58) NPY2RALDH1A1GPR119MEN1KMT2A
SCHEMBL22773246 0.93 MEN1 (0.60) NPY2RALDH1A1GPR119MEN1KMT2A
SCHEMBL22491552 0.93 MEN1 (0.60) NPY2RALDH1A1GPR119MEN1KMT2A
SCHEMBL16577073 0.87 GPR119 (0.61) NPY2RGPR119MEN1KMT2AKDM4E
SCHEMBL20602790 0.86 KMT2A (0.56) NPY2RGPR119MEN1KMT2AKDM4E
SCHEMBL22773288 0.86 RORC (0.55) NPY2RALDH1A1GPR119KDM4EPKM
SCHEMBL23212017 0.85 NPY2R (0.50) NPY2RALDH1A1GPR119KDM4EPKM
SCHEMBL30568007 0.85 NPY2R (0.50) NPY2RALDH1A1GPR119KDM4EPKM
SCHEMBL21752606 0.85 GPR119 (0.59) NPY2RGPR119MEN1KMT2AKDM4E
SCHEMBL19409663 0.85 GPR119 (0.59) NPY2RGPR119MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312499-A1 CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME H. LUNDBECK A/S (DK) 2023-10-05 US disclosed
US-20230312499-A1 CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME H. LUNDBECK A/S (DK) 2023-10-05 US disclosed
US-20230285378-A1 Anti-Viral Compounds ABBVIE INC. (US) 2023-09-14 US disclosed
US-20230285378-A1 Anti-Viral Compounds ABBVIE INC. (US) 2023-09-14 US disclosed
US-20230285378-A1 Anti-Viral Compounds ABBVIE INC. (US) 2023-09-14 US disclosed
US-11530189-B2 Carbamate compounds and methods of making and using same H. LUNDBECKA/S (DK) 2022-12-20 US disclosed
US-11214578-B2 Urea/carbamates FAAH MAGL or dual FAAH/MAGL inhibitors and uses thereof NORTHEASTERN UNIVERSITY (US) 2022-01-04 US disclosed
US-11214578-B2 Urea/carbamates FAAH MAGL or dual FAAH/MAGL inhibitors and uses thereof NORTHEASTERN UNIVERSITY (US) 2022-01-04 US disclosed
US-20210188793-A1 CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME LUNDBECK LA JOLLA RESEARCH CENTER, INC. 2021-06-24 US disclosed
US-11021453-B2 Carbamate compounds and methods of making and using same LUNDBECK LA JOLLA RESEARCH CENTER, INC. (US) 2021-06-01 US disclosed
US-20120004196-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2012-01-05 US disclosed
US-20120004196-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2012-01-05 US disclosed
US-20110207699-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2011-08-25 US disclosed
US-20110207699-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2011-08-25 US disclosed
US-20110207699-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2011-08-25 US disclosed
US-5962476-A FUNGICIDES KAKEN PHARMACEUTICAL CO., LTD. (JP) 1999-10-05 US disclosed
US-5716969-A FUNGICIDES KAKEN PHARMACEUTICAL CO., LTD. (JP) 1998-02-10 US disclosed
EP-0698606-B1 AZOLYLAMINE DERIVATIVE KAKEN PHARMA CO LTD (JP) 1997-12-17 EP disclosed
US-5620994-A FUNGICIDES KAKEN PHARMACEUTICAL CO., LTD. (JP) 1997-04-15 US disclosed
EP-0698606-A1 AZOLYLAMINE DERIVATIVE KAKEN PHARMACEUTICAL CO., LTD. (JP) 1996-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11530189-B2 Carbamate compounds and methods of making and using same ABHD6, ABHD16A, RABL6 NPY2R 4661/4885ALDH1A1 2487/4885GPR119 3853/4885
US-11214578-B2 Urea/carbamates FAAH MAGL or dual FAAH/MAGL inhibitors and uses thereof FAAH, FAAH2, MGLL NPY2R 1138/4885ALDH1A1 687/4885GPR119 568/4885
US-11021453-B2 Carbamate compounds and methods of making and using same ABHD6, ABHD16A, RABL6 NPY2R 4654/4885ALDH1A1 2385/4885GPR119 3935/4885
US-20210188793-A1 CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME ABHD6, ABHD16A, RABL6 NPY2R 4661/4885ALDH1A1 2487/4885GPR119 3853/4885
US-20230285378-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS NPY2R 4860/4885ALDH1A1 2858/4885GPR119 3832/4885
US-20230312499-A1 CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME ABHD6, ABHD16A, RABL6 NPY2R 4661/4885ALDH1A1 2487/4885GPR119 3853/4885
US-20110207699-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS NPY2R 4860/4885ALDH1A1 2858/4885GPR119 3832/4885
US-20120004196-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS NPY2R 4860/4885ALDH1A1 2858/4885GPR119 3832/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.