Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574362 | 0.89 | KMT2A (0.50) | KMT2APOLBALDH1A1CYP2C19TP53 | |
| SCHEMBL15568595 | 0.89 | KMT2A (0.62) | KMT2APOLBALDH1A1CYP2C19TP53 | |
| SCHEMBL4400952 | 0.83 | KMT2A (0.62) | KMT2APOLBALDH1A1CYP2C19TP53 | |
| SCHEMBL14426922 | 0.82 | KMT2A (0.62) | KMT2APOLBALDH1A1CYP2C19TP53 | |
| SCHEMBL1202589 | 0.80 | RECQL (0.46) | KMT2APOLBALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL15568723 | 0.80 | KMT2A (0.43) | KMT2APOLBCA1CA2CA9 | |
| SCHEMBL15568647 | 0.80 | USP2 (0.44) | KMT2APOLBALDH1A1CYP2C19TP53 | |
| SCHEMBL13870211 | 0.79 | KMT2A (1.00) | KMT2APOLBALDH1A1CYP2C19TP53 | |
| SCHEMBL10482000 | 0.79 | CA1 (0.50) | KMT2APOLBALDH1A1CA1CA2 | |
| SCHEMBL10289671 | 0.79 | KMT2A (0.58) | KMT2APOLBALDH1A1CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882727-B1 | IMMUNOMODULATORY COMPOUNDS | UNIV STRATHCLYDE (GB) | 2021-01-20 | — | — | EP | disclosed |
| EP-2882727-B1 | IMMUNOMODULATORY COMPOUNDS | UNIV STRATHCLYDE (GB) | 2021-01-20 | — | — | EP | disclosed |
| US-9598386-B2 | Immunomodulatory compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2017-03-21 | — | — | US | disclosed |
| US-9598386-B2 | Immunomodulatory compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2017-03-21 | — | — | US | disclosed |
| US-9598386-B2 | Immunomodulatory compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2017-03-21 | — | — | US | disclosed |
| US-20150218116-A1 | Immunomodulatory Compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2015-08-06 | — | — | US | disclosed |
| US-20150218116-A1 | Immunomodulatory Compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2015-08-06 | — | — | US | disclosed |
| US-20150218116-A1 | Immunomodulatory Compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2015-08-06 | — | — | US | disclosed |
| EP-2882727-A1 | IMMUNOMODULATORY COMPOUNDS | University of Strathclyde (GB) | 2015-06-17 | — | — | EP | disclosed |
| WO-2014023934-A1 | IMMUNOMODULATORY COMPOUNDS | UNIVERSITY OF STRATHCLYDE (GB) | 2014-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150218116-A1 | Immunomodulatory Compounds | TSLP, IL2, ICOS | KMT2A 3352/4885POLB 3712/4885ALDH1A1 1333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.