Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574362 | 0.89 | KMT2A (0.50) | KMT2AMMP1MMP2MMP9MMP13 | |
| SCHEMBL1138688 | 0.83 | PLCG1 (0.46) | KMT2AMMP1MMP2MMP9MMP13 | |
| SCHEMBL14426941 | 0.80 | KMT2A (0.43) | KMT2AMMP1MMP2MMP9MMP13 | |
| SCHEMBL1202589 | 0.80 | RECQL (0.46) | KMT2AMMP1MMP2MMP9MMP13 | |
| SCHEMBL15568656 | 0.80 | KMT2A (0.66) | KMT2APOLBCA2CA1CA9 | |
| SCHEMBL15568647 | 0.80 | USP2 (0.44) | KMT2AEGFRERBB2POLBMEN1 | |
| SCHEMBL10482000 | 0.79 | CA1 (0.50) | KMT2AMMP1MMP2MMP9MMP13 | |
| SCHEMBL21928927 | 0.78 | CA12 (0.43) | MMP2EGFRERBB2CA2CA1 | |
| SCHEMBL8997396 | 0.77 | TSHR (0.50) | KMT2APOLBCA2CA1CA9 | |
| SCHEMBL20155480 | 0.77 | PLCG1 (0.41) | KMT2AEGFRERBB2PLCG1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882727-B1 | IMMUNOMODULATORY COMPOUNDS | UNIV STRATHCLYDE (GB) | 2021-01-20 | — | — | EP | disclosed |
| EP-2882727-B1 | IMMUNOMODULATORY COMPOUNDS | UNIV STRATHCLYDE (GB) | 2021-01-20 | — | — | EP | disclosed |
| US-9598386-B2 | Immunomodulatory compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2017-03-21 | — | — | US | disclosed |
| US-9598386-B2 | Immunomodulatory compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2017-03-21 | — | — | US | disclosed |
| US-9598386-B2 | Immunomodulatory compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2017-03-21 | — | — | US | disclosed |
| US-20150218116-A1 | Immunomodulatory Compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2015-08-06 | — | — | US | disclosed |
| US-20150218116-A1 | Immunomodulatory Compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2015-08-06 | — | — | US | disclosed |
| US-20150218116-A1 | Immunomodulatory Compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2015-08-06 | — | — | US | disclosed |
| EP-2882727-A1 | IMMUNOMODULATORY COMPOUNDS | University of Strathclyde (GB) | 2015-06-17 | — | — | EP | disclosed |
| WO-2014023934-A1 | IMMUNOMODULATORY COMPOUNDS | UNIVERSITY OF STRATHCLYDE (GB) | 2014-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150218116-A1 | Immunomodulatory Compounds | TSLP, IL2, ICOS | KMT2A 3352/4885MMP1 1728/4885MMP2 3158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.