Prednisolone Phosphoric Acid

SCHEMBL15568676

C[C@]12C=CC(=O)C=C1CCC1C2C(O)C[C@@]2(C)C1CC[C@]2(O)C(=O)COP(=O)([O-])O.C[C@]12C=CC(=O)C=C1CCC1C2C(O)C[C@@]2(C)C1CC[C@]2(O)C(=O)COP(=O)([O-])O.[Na+].[Na+]

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

NR3C1

The experimentally established mechanism targets of Prednisolone Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

	gene	UniProt	supporting neighbours	confidence
▸	NR3C1 known ✓	P04150	13/20	0.72

▸	PGR	P06401	4/20	0.75

▸	HIF1A	Q16665	3/20	0.75

▸	HSD17B10	Q99714	2/20	0.72

▸	CYP3A4	P08684	2/20	0.72

▸	AR	P10275	2/20	0.72

▸	ABCB11	O95342	1/20	0.72

▸	TNF	P01375	1/20	0.72

▸	IL6	P05231	1/20	0.72

▸	SERPINA6	P08185	1/20	0.72

▸	NR3C2	P08235	1/20	0.72

▸	GLUL	P15104	1/20	0.72

▸	ADAM17	P78536	1/20	0.72

▸	GPBAR1	Q8TDU6	1/20	0.72

▸	CYP2C19	P33261	1/20	0.72

▸	LMNA	P02545	1/20	0.72

▸	KMT2A	Q03164	1/20	0.57

▸	F2	P00734	1/20	0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Prednisolone Phosphoric Acid SCHEMBL23563	0.95	PGR (0.77)	PGRHIF1ANR3C1HSD17B10CYP3A4
Prednisolone Phosphoric Acid SCHEMBL1650407	0.95	PGR (0.77)	PGRHIF1ANR3C1HSD17B10CYP3A4
Prednisolone Phosphoric Acid SCHEMBL1270166	0.95	PGR (0.77)	PGRHIF1ANR3C1HSD17B10CYP3A4
Prednisolone Phosphoric Acid SCHEMBL136773	0.93	PGR (0.78)	PGRHIF1ANR3C1HSD17B10CYP3A4
Prednisolone Phosphoric Acid SCHEMBL21152848	0.93	PGR (0.78)	PGRHIF1ANR3C1HSD17B10CYP3A4
Prednisolone Phosphoric Acid SCHEMBL24622433	0.93	PGR (0.78)	PGRHIF1ANR3C1HSD17B10CYP3A4
Prednisolone Phosphoric Acid SCHEMBL21152533	0.93	PGR (0.78)	PGRHIF1ANR3C1HSD17B10CYP3A4
Prednisolone Phosphoric Acid SCHEMBL13130881	0.93	PGR (0.78)	PGRHIF1ANR3C1HSD17B10CYP3A4
SCHEMBL3634790	0.93	PGR (0.78)	PGRHIF1ANR3C1HSD17B10CYP3A4
Prednisolone Phosphoric Acid SCHEMBL20451347	0.93	PGR (0.78)	PGRHIF1ANR3C1HSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2014027006-A1	BIOADHESIVE FORMULATIONS FOR USE IN DRUG DELIVERY	EDKO PAZARLAMA TANITIM TICARET LIMITED SIRKETI (TR)	2014-02-20	—	—	WO	disclosed