Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19043113 | 0.84 | KMT2A (0.49) | ALDH1A1KMT2AMEN1TTRSMN1; SMN2 | |
| SCHEMBL10728171 | 0.84 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1PPARGPPARD | |
| SCHEMBL3719886 | 0.83 | TTR (0.42) | ALDH1A1KMT2AMEN1PPARGPPARD | |
| SCHEMBL30644304 | 0.82 | ALDH1A1 (0.69) | ALDH1A1KMT2AMEN1PPARGPPARD | |
| SCHEMBL557409 | 0.82 | ALDH1A1 (0.69) | ALDH1A1KMT2AMEN1PPARGPPARD | |
| SCHEMBL8431075 | 0.82 | LMNA (0.49) | ALDH1A1KMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL2097147 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1TTRSMN1; SMN2 | |
| SCHEMBL1015099 | 0.81 | KMT2A (0.56) | ALDH1A1KMT2AMEN1PPARGPPARD | |
| SCHEMBL3343652 | 0.81 | ALDH1A1 (0.67) | ALDH1A1KMT2AMEN1PPARGPPARD | |
| SCHEMBL3940203 | 0.81 | CSNK2A1 (0.66) | KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017182945-A1 | FLUORESCENT COMPOUNDS, PRODUCTION METHODS AND USES THEREOF | UNIVERSIDADE DE AVEIRO (PT) | 2017-10-26 | — | — | WO | claimed |
| EP-3732167-A2 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BioMarin Pharmaceutical Inc. (US) | 2020-11-04 | — | — | EP | disclosed |
| WO-2017182945-A1 | FLUORESCENT COMPOUNDS, PRODUCTION METHODS AND USES THEREOF | UNIVERSIDADE DE AVEIRO (PT) | 2017-10-26 | — | — | WO | disclosed |
| EP-3166937-A1 | ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF | Celgene Corporation (US) | 2017-05-17 | — | — | EP | disclosed |
| WO-2016007848-A1 | ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF | CELGENE CORPORATION (US) | 2016-01-14 | — | — | WO | disclosed |
| EP-2303863-A1 | 5- AND 6-MEMBERED HETEROCYCLIC COMPOUNDS | Envivo Pharmaceuticals, Inc. (US) | 2011-04-06 | — | — | EP | disclosed |
| WO-2009158473-A1 | 5- AND 6-MEMBERED HETEROCYCLIC COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-12-30 | — | — | WO | disclosed |
| US-4386206-A | Tertiary amides as solvents in anthrapyridone syntheses | DYNAPOL (US) | 1983-05-31 | — | — | US | disclosed |