Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.58 |
| ▸ | HNF4A | P41235 | 1/20 | 0.54 |
| ▸ | DDT | P30046 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | FABP3 | P05413 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | BLVRB | P30043 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | UCHL5 | Q9Y5K5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29400093 | 0.88 | KMO (0.63) | KMOHNF4ADDTFOLH1RXRA | |
| SCHEMBL2947834 | 0.88 | KMO (0.63) | KMOHNF4ADDTFOLH1RXRA | |
| SCHEMBL225203 | 0.86 | HNF4A (0.71) | HNF4AALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL21801848 | 0.84 | KMO (0.69) | KMOHNF4ADDTFOLH1RXRA | |
| SCHEMBL2213546 | 0.84 | KMO (0.73) | KMODDTFOLH1RXRARXRB | |
| SCHEMBL30259065 | 0.84 | KMO (0.73) | KMODDTFOLH1RXRARXRB | |
| SCHEMBL1707626 | 0.82 | KMO (0.70) | KMODDTFOLH1RXRARXRB | |
| SCHEMBL382724 | 0.82 | KMO (0.70) | KMODDTFOLH1RXRARXRB | |
| SCHEMBL28467375 | 0.81 | FOLH1 (0.60) | KMOHNF4ADDTFOLH1RXRA | |
| SCHEMBL28124542 | 0.81 | KMO (0.63) | KMOHNF4ADDTFOLH1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266737-B2 | Adsorption systems using metal-organic frameworks | ARKEMA INC. (US) | 2019-04-23 | — | — | US | disclosed |
| US-20150291870-A1 | ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS | ARKEMA INC. | 2015-10-15 | — | — | US | disclosed |
| EP-2885365-A2 | ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS | Arkema, Inc. (US) | 2015-06-24 | — | — | EP | disclosed |
| WO-2014028574-A9 | ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS | ARKEMA INC. (US) | 2015-04-02 | — | — | WO | disclosed |
| WO-2014028574-A2 | ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS | ARKEMA INC. (US) | 2014-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291870-A1 | ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS | PFAS, CHIA, PARN | KMO 1005/4885HNF4A 457/4885DDT 1120/4885 |
| US-10266737-B2 | Adsorption systems using metal-organic frameworks | PFAS, CHIA, PARN | KMO 1005/4885HNF4A 457/4885DDT 1120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.