Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15569843 | 0.85 | MAPT (0.34) | KDM4ESMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL15569312 | 0.81 | KDM4E (0.41) | KDM5BKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL15569784 | 0.78 | LMNA (0.32) | SMN1; SMN2LMNA | |
| SCHEMBL15568782 | 0.75 | KDM4E (0.43) | KDM5BKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL15569361 | 0.74 | MEN1 (0.39) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL15570066 | 0.72 | ADORA1 (0.45) | KDM5BKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL17430005 | 0.72 | KDM4E (0.47) | KDM4EMEN1KMT2ALMNAMAPT | |
| SCHEMBL387677 | 0.72 | SMN1; SMN2 (0.42) | KDM5BKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL15570276 | 0.71 | KDM4E (0.41) | KDM5BKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL22900489 | 0.71 | KMT2A (0.46) | KDM4ESMN1; SMN2KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014031971-A1 | HERBICIDAL PYRIDAZINONES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-02-27 | — | — | WO | disclosed |