SCHEMBL15569784

SCHEMBL15569784

C=CCOc1c(C)c(C(=O)OC2=CC(=O)CCC2)nn(C)c1=O

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15569397 0.78 KDM5B (0.38) LMNASMN1; SMN2
SCHEMBL15569366 0.77 MAPT (0.31) LMNASMN1; SMN2
SCHEMBL15569843 0.76 MAPT (0.34) LMNATSHRSMN1; SMN2HSD17B10
SCHEMBL15569494 0.75 TP53 (0.33)
SCHEMBL15569361 0.74 MEN1 (0.39) LMNA
SCHEMBL15570307 0.74 TP53 (0.44) LMNASMN1; SMN2
SCHEMBL15569514 0.73 ATM (0.38) SMN1; SMN2
SCHEMBL15570064 0.69 TP53 (0.43) LMNASMN1; SMN2
SCHEMBL15569628 0.65 TP53 (0.41) LMNASMN1; SMN2
SCHEMBL15569312 0.62 KDM4E (0.41) LMNASMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014031971-A1 HERBICIDAL PYRIDAZINONES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-02-27 WO disclosed