SCHEMBL15569366

SCHEMBL15569366

CCCc1c(C)c(C(=O)OC2=CC(=O)CCC2)nn(C)c1=O

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15570307 0.77 TP53 (0.44) MAPTSMN1; SMN2MEN1LMNAKMT2A
SCHEMBL15570276 0.77 KDM4E (0.41) MAPTSMN1; SMN2MEN1LMNAKMT2A
SCHEMBL15569784 0.77 LMNA (0.32) SMN1; SMN2LMNA
SCHEMBL15569514 0.76 ATM (0.38) MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL15569737 0.72 POLB (0.34) MAPTSMN1; SMN2MEN1LMNAKMT2A
SCHEMBL15569494 0.72 TP53 (0.33) MAPT
SCHEMBL15570064 0.70 TP53 (0.43) MAPTSMN1; SMN2MEN1LMNAKMT2A
SCHEMBL15569628 0.68 TP53 (0.41) MAPTSMN1; SMN2MEN1LMNAKMT2A
SCHEMBL15569660 0.66 KDM5B (0.42) MAPTSMN1; SMN2MEN1LMNAKMT2A
SCHEMBL15570041 0.66 ALDH1A1 (0.39) SMN1; SMN2MEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014031971-A1 HERBICIDAL PYRIDAZINONES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-02-27 WO disclosed