Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | NOS2 | P35228 | 1/20 | 0.52 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18872352 | 0.87 | KMT2A (0.61) | KMT2AMEN1NOS2KDM4EALDH1A1 | |
| SCHEMBL6439288 | 0.82 | ALDH1A1 (0.68) | KMT2AMEN1NOS2RAD51KDM4E | |
| SCHEMBL27936975 | 0.79 | NPC1 (0.47) | KMT2AMEN1NOS2KDM4EALDH1A1 | |
| SCHEMBL1104841 | 0.79 | MEN1 (1.00) | KMT2AMEN1MAPK1KDM4EALDH1A1 | |
| SCHEMBL12116702 | 0.76 | ESR2 (0.65) | KMT2AMEN1RAD51MAPK1KDM4E | |
| SCHEMBL26114611 | 0.75 | RAD51 (0.55) | KMT2AMEN1NOS2RAD51KDM4E | |
| SCHEMBL19820193 | 0.74 | NOS2 (0.55) | KMT2AMEN1NOS2MAPK1KDM4E | |
| SCHEMBL26350319 | 0.73 | ESR2 (0.61) | KMT2AMEN1MAPK1KDM4EALDH1A1 | |
| SCHEMBL29412068 | 0.72 | ALDH1A1 (0.82) | KDM4EALDH1A1NPC1TP53SMN1; SMN2 | |
| SCHEMBL4556394 | 0.71 | KMT2A (0.44) | KMT2AMEN1RAD51MAPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014028931-A2 | COMPOUNDS AND METHODS FOR TREATING MAMMALIAN GASTROINTESTINAL MICROBIAL INFECTIONS | BRANDEIS UNIVERSITY (US) | 2014-02-20 | — | — | WO | disclosed |