SCHEMBL6439288

SCHEMBL6439288

Nc1ccc(-c2nc3ccccc3n2N)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.68
KDM4E B2RXH2 7/20 0.68
RAB9A P51151 7/20 0.68
NPC1 O15118 6/20 0.68
TP53 P04637 4/20 0.68
PKM P14618 3/20 0.68
HSD17B10 Q99714 3/20 0.68
GAA P10253 2/20 0.68
ALOX15 P16050 1/20 0.68
HPGD P15428 5/20 0.62
SMN1; SMN2 Q16637 5/20 0.57
MAPT P10636 3/20 0.57
NOS2 P35228 1/20 0.56
RAD51 Q06609 1/20 0.51
KMT2A Q03164 5/20 0.47
MEN1 O00255 4/20 0.46
LMNA P02545 2/20 0.46
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18872352 0.87 KMT2A (0.61) ALDH1A1KDM4ERAB9ANPC1TP53
SCHEMBL15569893 0.82 KMT2A (0.65) ALDH1A1KDM4ERAB9ANPC1TP53
SCHEMBL26114611 0.81 RAD51 (0.55) ALDH1A1KDM4ERAB9ANPC1TP53
SCHEMBL9520082 0.81 KDM4E (0.71) ALDH1A1KDM4ERAB9ANPC1TP53
SCHEMBL9705114 0.81 ALDH1A1 (1.00) ALDH1A1KDM4ERAB9ANPC1TP53
SCHEMBL31474745 0.81 ALDH1A1 (1.00) ALDH1A1KDM4ERAB9ANPC1TP53
SCHEMBL27936975 0.79 NPC1 (0.47) ALDH1A1KDM4ERAB9ANPC1TP53
SCHEMBL2605804 0.78 ESR1 (0.63) ALDH1A1KDM4ERAB9ANPC1TP53
SCHEMBL21777019 0.77 KDM4E (1.00) ALDH1A1KDM4ERAB9ANPC1TP53
SCHEMBL11955410 0.77 ESR1 (0.61) ALDH1A1KDM4ERAB9ANPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346755-A1 PEEK Compositions with Reduced Crystallization Rate DUPONT SAFETY & CONTSTRUCTION INC (US) 2025-11-13 US claimed
EP-2802694-B1 METHOD FOR REMOVING SULFUR FROM FIBER USING A WEAK BASE DUPONT SAFETY & CONSTRUCTION INC (US) 2024-05-08 EP claimed
CN-116656126-A Preparation method and application of quaternized polyimide film 西南科技大学 2023-08-29 CN claimed
US-11279800-B2 Aramid copolymer yarn having low residual sulfur DUPONT SAFETY & CONSTRUCTION, INC. (US) 2022-03-22 US claimed
EP-2802697-A1 SULFUR-CONTAINING IMIDAZOLE FIBER HAVING IONICALLY BONDED HALIDES E. I. Du Pont de Nemours and Company (US) 2014-11-19 EP claimed
EP-2802698-A1 SULFUR AND ALKALI METAL CONTAINING IMIDAZOLE FIBER HAVING IONICALLY BOUND HALIDES E. I. Du Pont de Nemours and Company (US) 2014-11-19 EP claimed
EP-2802700-A1 ARAMID COPOLYMER YARN HAVING LOW RESIDUAL SULFUR E. I. Du Pont de Nemours and Company (US) 2014-11-19 EP claimed
WO-2013105944-A1 SULFUR AND ALKALI METAL CONTAINING IMIDAZOLE FIBER HAVING IONICALLY BOUND HALIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-07-18 WO claimed
WO-2013105948-A1 ARAMID COPOLYMER YARN HAVING LOW RESIDUAL SULFUR E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-07-18 WO claimed
WO-2013105940-A1 SULFUR-CONTAINING IMIDAZOLE FIBER HAVING IONICALLY BONDED HALIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-07-18 WO claimed
US-20250346755-A1 PEEK Compositions with Reduced Crystallization Rate DUPONT SAFETY & CONTSTRUCTION INC (US) 2025-11-13 US disclosed
EP-3329039-B1 YARN FROM POLYMERS HAVING DIFFERENT DECOMPOSITION TEMPERATURES AND PROCESS FOR FORMING SAME DUPONT SAFETY & CONSTRUCTION INC (US) 2024-09-25 EP disclosed
EP-4193016-B1 PAPER COMPRISING ARAMID PULP SUITABLE FOR ELECTROCHEMICAL CELLS, AND ELECTROCHEMICAL CELLS MADE THEREFROM DUPONT SAFETY & CONSTRUCTION INC (US) 2024-07-17 EP disclosed
EP-2802694-B1 METHOD FOR REMOVING SULFUR FROM FIBER USING A WEAK BASE DUPONT SAFETY & CONSTRUCTION INC (US) 2024-05-08 EP disclosed
CN-116656126-A Preparation method and application of quaternized polyimide film 西南科技大学 2023-08-29 CN disclosed
WO-2012097266-A1 COPOLYMER FIBERS AND PROCESSES FOR MAKING SAME E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-07-19 WO disclosed
WO-2012097254-A1 PRODUCTION OF AND DRYING OF COPOLYMER FIBERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-07-19 WO disclosed
WO-2012097249-A1 PRODUCTION OF AND DRYING OF COPOLYMER FIBERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-07-19 WO disclosed
EP-1533332-A1 NOVEL POLYIMIDE COPOLYMER AND METAL LAMINATE COMPRISING THE SAME Nippon Mektron, Limited (JP) 2005-05-25 EP disclosed
US-20040180227-A1 Novel polyimide copolymer and metal laminate using the same NIPPON MEKTRON LIMITED (JP) 2004-09-16 US disclosed