SCHEMBL15570448

SCHEMBL15570448

O=[SH](=O)Oc1ccccc1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HPGD P15428 2/20 0.41
TSHR P16473 1/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
PKM P14618 1/20 0.39
CXCL8 P10145 1/20 0.39
HTT P42858 2/20 0.37
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
KCNH2 Q12809 1/20 0.37
TP53 P04637 1/20 0.37
SLC6A4 P31645 3/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A3 Q01959 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
PTK2B Q14289 1/20 0.36
MAPT P10636 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27531256 0.82 RHEB (0.43) LMNASMN1; SMN2TSHRKMT2AHTT
SCHEMBL17469707 0.82 CA1 (0.38) LMNASMN1; SMN2HPGDTSHRKMT2A
SCHEMBL27917635 0.77 RHEB (0.40) LMNASMN1; SMN2HPGDTSHRMEN1
SCHEMBL27986003 0.71 TSHR (0.43) LMNASMN1; SMN2HPGDTSHRMEN1
SCHEMBL17202008 0.71 FABP7 (0.35)
SCHEMBL28136946 0.71 ALDH1A1 (0.50) LMNASMN1; SMN2TSHRL3MBTL1MAPT
SCHEMBL14578683 0.71 CA1 (0.62) LMNASMN1; SMN2TSHRKMT2AHTT
SCHEMBL14142067 0.71 TDP1 (0.46) LMNAHPGDTSHRMEN1KMT2A
SCHEMBL7769417 0.71 TSHR (0.53) LMNASMN1; SMN2HPGDTSHRMEN1
SCHEMBL1436765 0.71 HPGD (0.59) LMNASMN1; SMN2HPGDTSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108203408-A A kind of pyrazole compound containing N- aromatic yl sulphonates and its synthesis and application 兰州大学 2018-06-26 CN disclosed
US-9394245-B2 Process for sulfonating halobenzene derivatives with sulfur trioxide SOLVAY SPECIALTY POLYMERS USA, LLC. (US) 2016-07-19 US disclosed
US-20150191425-A1 PROCESS FOR SULFONATING HALOBENZENE DERIVATIVES WITH SULFUR TRIOXIDE SOLVAY SPECIALTY POLYMERS USA, LLC. (US) 2015-07-09 US disclosed
EP-2885273-A1 PROCESS FOR SULFONATING HALOBENZENE DERIVATIVES WITH SULFUR TRIOXIDE Solvay Specialty Polymers USA, LLC. (US) 2015-06-24 EP disclosed
WO-2014029666-A1 PROCESS FOR SULFONATING HALOBENZENE DERIVATIVES WITH SULFUR TRIOXIDE SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2014-02-27 WO disclosed