Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 2/20 | 0.65 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15575117 | 1.00 | SLC5A1 (0.65) | SLC5A1SLC5A2CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL29396796 | 0.85 | MAPT (0.68) | SLC5A1SLC5A2CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL662966 | 0.85 | MAPT (0.74) | CYP2C19CYP19A1CYP2C9MAOAMAOB | |
| SCHEMBL662967 | 0.85 | MAPT (0.74) | CYP2C19CYP19A1CYP2C9MAOAMAOB | |
| SCHEMBL15598378 | 0.83 | ABCB1 (0.70) | SLC5A1SLC5A2CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL29435902 | 0.83 | ABCB1 (0.70) | SLC5A1SLC5A2CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL25234449 | 0.83 | SLC5A1 (0.76) | SLC5A1SLC5A2CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL17483792 | 0.83 | SLC5A1 (0.76) | SLC5A1SLC5A2CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL8252412 | 0.81 | CYP19A1 (0.68) | SLC5A1SLC5A2CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL17265614 | 0.79 | ABCB1 (0.72) | SLC5A1SLC5A2CYP2C19CYP19A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2888012-B1 | ORAL CARE | UNIV PRETORIA (ZA) | 2020-06-17 | — | — | EP | disclosed |
| EP-2888012-A2 | ORAL CARE | University of Pretoria (ZA) | 2015-07-01 | — | — | EP | disclosed |
| US-20150174059-A1 | ORAL CARE | UNIVERSITY OF PRETORIA (ZA) | 2015-06-25 | — | — | US | disclosed |
| WO-2014033625-A2 | ORAL CARE | UNIVERSITY OF PRETORIA (ZA) | 2014-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150174059-A1 | ORAL CARE | NOP2, POLR1C, DPM1 | SLC5A1 4623/4885SLC5A2 4424/4885CYP2C19 715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.