Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 4/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31731178 | 0.89 | ALDH1A1 (0.47) | GAAL3MBTL1ICMTOPRM1ALDH1A1 | |
| SCHEMBL31731479 | 0.88 | GAA (0.42) | GAAL3MBTL1ICMTHTTMEN1 | |
| SCHEMBL15577185 | 0.88 | GAA (0.44) | GAAL3MBTL1ICMTTSHRMAPT | |
| SCHEMBL31731594 | 0.87 | ICMT (0.41) | GAAL3MBTL1ICMT | |
| SCHEMBL18112397 | 0.85 | OPRM1 (0.41) | GAAOPRM1ALDH1A1HTTMAPT | |
| SCHEMBL627890 | 0.82 | OPRM1 (0.43) | GAAOPRM1ALDH1A1HTTMAPT | |
| SCHEMBL12542222 | 0.80 | OPRM1 (0.40) | GAAICMTOPRM1ALDH1A1TSHR | |
| SCHEMBL12542588 | 0.77 | OPRM1 (0.40) | OPRM1ALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL20902327 | 0.76 | OPRM1 (0.39) | GAAL3MBTL1OPRM1HTTMAPT | |
| SCHEMBL12540893 | 0.76 | OPRM1 (0.39) | OPRM1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014041349-A1 | TETRAHYDROPYRAN-4-YLETHYLAMINO- OR TETRAHYDROPYRANYL-4-ETHYLOXY-PYRIMIDINES OR -PYRIDAZINES AS ISOPRENYLCYSTEINCARBOXYMETHYL TRANSFERASE INHIBITORS | CANCER THERAPEUTICS CRC PTY LTD (AU) | 2014-03-20 | — | — | WO | disclosed |
| WO-2014041349-A1 | TETRAHYDROPYRAN-4-YLETHYLAMINO- OR TETRAHYDROPYRANYL-4-ETHYLOXY-PYRIMIDINES OR -PYRIDAZINES AS ISOPRENYLCYSTEINCARBOXYMETHYL TRANSFERASE INHIBITORS | CANCER THERAPEUTICS CRC PTY LTD (AU) | 2014-03-20 | — | — | WO | disclosed |