SCHEMBL15577401

SCHEMBL15577401

Cc1cccc(Nc2ncc(-c3ccncc3)s2)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 12/20 0.63
RAB9A P51151 3/20 0.61
HDAC6 Q9UBN7 2/20 0.61
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
MAPT P10636 1/20 0.61
MAPK1 P28482 1/20 0.61
HTT P42858 1/20 0.61
NPC1 O15118 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
LIMK1 P53667 1/20 0.51
LATS1 O95835 1/20 0.48
ABL1 P00519 2/20 0.47
HDAC3 O15379 1/20 0.47
PDGFRB P09619 1/20 0.47
HDAC4 P56524 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC10 Q969S8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13524909 0.81 KDR (0.80) KDRRAB9AMEN1KMT2ANPC1
SCHEMBL6328806 0.78 KDR (0.71) KDRRAB9ANPC1SMN1; SMN2ABL1
SCHEMBL6330404 0.78 KDR (1.00) KDRLIMK1NAMPT
SCHEMBL1884904 0.77 MAPT (0.64) RAB9AHDAC6MEN1KMT2AMAPT
SCHEMBL4601487 0.77 RAB9A (0.62) KDRRAB9AHDAC6MEN1KMT2A
SCHEMBL996232 0.76 RAB9A (1.00) RAB9AHDAC6MEN1KMT2AMAPT
SCHEMBL6181301 0.75 KDR (0.82) KDRRAB9AMEN1KMT2AMAPT
SCHEMBL3651635 0.74 KDR (1.00) KDRNAMPT
SCHEMBL10569930 0.73 NPSR1 (0.70) KDRRAB9AHDAC6MEN1KMT2A
SCHEMBL5889064 0.73 KIT (0.62) KDRLIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3964206-A1 COMPOUNDS FOR THE TREATMENT OF COVID-19 Dompe' Farmaceutici S.P.A. (IT) 2022-03-09 EP claimed
US-12448437-B2 Transplant tolerance induction with carbodiimide treated tolerizing vaccine REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2025-10-21 US disclosed
WO-2025215206-A1 ACTIVATOR OF PRIMARY CILIA TO TREAT COGNITIVE DYSFUNCTIONS OR CILIOPATHIES Institut National de la Santé et de la Recherche Médicale (FR) 2025-10-16 WO disclosed
EP-4615869-A1 COMBINATION THERAPY COMPRISING BISPECIFIC ANTIBODIES COMPRISING AN NRP1 BINDING DOMAIN Pinetree Therapeutics, Inc. (US) 2025-09-17 EP disclosed
US-20250213601-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES Didenko, Kirill (US) 2025-07-03 US disclosed
CN-120091810-A Methods and highly bioavailable permeable compounds for treating viral diseases 基里尔·迪丹克 2025-06-03 CN disclosed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 WO disclosed
EP-4417212-A2 TRANSPLANT TOLERANCE INDUCTION WITH CARBODIIMIDE TREATED TOLERIZING VACCINE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2024-08-21 EP disclosed
WO-2024102187-A1 COMBINATION THERAPY COMPRISING BISPECIFIC ANTIBODIES COMPRISING AN NRP1 BINDING DOMAIN PINETREE THERAPEUTICS, INC. (US) 2024-05-16 WO disclosed
US-20240145038-A1 cfDNA FRAGMENTOMIC DETECTION OF CANCER WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2024-05-02 US disclosed
WO-2016144569-A1 METHODS AND COMPOSITIONS FOR TREATING SKIN TO RESOLVE INFLAMMATION AND SCREENING FOR ACTIVES THAT STIMULATE PRO-RESOLUTION PATHWAYS ELC MANAGEMENT LLC (US) 2016-09-15 WO disclosed
EP-2941241-A1 METHOD AND COMPOSITIONS FOR IMPROVING SELECTIVE CATABOLYSIS AND VIABILITY IN CELLS OF KERATIN SURFACES ELC Management LLC (US) 2015-11-11 EP disclosed
US-20150313830-A1 Method And Compositions For Improving Selective Catabolysis And Viability In Cells Of Keratin Surfaces ELC MAN LLC (US) 2015-11-05 US disclosed
CN-104902872-A Methods and compositions for improving selective catabolism and viability in cells on the surface of keratin ELC MAN LLC 2015-09-09 CN disclosed
EP-2897582-A1 METHOD AND COMPOSITIONS FOR IMPROVING SELECTIVE CATABOLYSIS IN CELLS OF KERATIN SURFACES ELC Management LLC (US) 2015-07-29 EP disclosed
CN-104797237-A Methods and compositions for improving selective catabolism in cells on the surface of keratin ELC MAN LLC 2015-07-22 CN disclosed
US-20150071895-A1 Method And Compositions For Improving Selective Catabolysis in Cells Of Keratin Surfaces PERNODET NADINE A (US) 2015-03-12 US disclosed
US-20140193391-A1 Method And Compositions For Improving Selective Catabolysis And Viability In Cells Of Keratin Surfaces ELC MAN LLC (US) 2014-07-10 US disclosed
WO-2014107411-A1 METHOD AND COMPOSITIONS FOR IMPROVING SELECTIVE CATABOLYSIS AND VIABILITY IN CELLS OF KERATIN SURFACES ELC MANAGEMENT LLC (US) 2014-07-10 WO disclosed
WO-2014043009-A1 METHOD AND COMPOSITIONS FOR IMPROVING SELECTIVE CATABOLYSIS IN CELLS OF KERATIN SURFACES ELC MANAGEMENT LLC (US) 2014-03-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150313830-A1 Method And Compositions For Improving Selective Catabolysis And Viability In Cells Of Keratin Surfaces KRT18, CTSA, UNG KDR 2309/4885RAB9A 2161/4885HDAC6 217/4885
US-20150071895-A1 Method And Compositions For Improving Selective Catabolysis in Cells Of Keratin Surfaces KRT18, ATG7, SQSTM1 KDR 3123/4885RAB9A 2364/4885HDAC6 80/4885
US-20140193391-A1 Method And Compositions For Improving Selective Catabolysis And Viability In Cells Of Keratin Surfaces KRT18, BECN1, CTSA KDR 2326/4885RAB9A 3292/4885HDAC6 105/4885
US-20250213601-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES ACE2, FURIN, SARS1 KDR 45/4885RAB9A 1443/4885HDAC6 2650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.