Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL761081 | 0.93 | LMNA (0.38) | HTR3ALMNAKMT2AMEN1ABCC4 | |
| SCHEMBL710379 | 0.91 | HTR3A (0.37) | HTR3ALMNAKMT2AMEN1ABCC4 | |
| Vosaroxin SCHEMBL15933161 | 0.89 | HTR3A (0.35) | HTR3ALMNAKMT2AMEN1ABCC4 | |
| Vosaroxin SCHEMBL3207291 | 0.89 | HTR3A (0.35) | HTR3ALMNAKMT2AMEN1ABCC4 | |
| SCHEMBL12055755 | 0.89 | HTR3A (0.35) | HTR3ALMNAKMT2AMEN1ABCC4 | |
| Vosaroxin SCHEMBL195037 | 0.89 | HTR3A (0.35) | HTR3ALMNAKMT2AMEN1ABCC4 | |
| Vosaroxin SCHEMBL674441 | 0.89 | HTR3A (0.35) | HTR3ALMNAKMT2AMEN1ABCC4 | |
| SCHEMBL15802906 | 0.89 | EPHA2 (0.36) | HTR3ALMNAKMT2AMEN1ABCC4 | |
| Vosaroxin SCHEMBL18694851 | 0.88 | HTR3A (0.35) | HTR3ALMNAKMT2AMEN1ABCC4 | |
| Hydrochloric Acid SCHEMBL7835838 | 0.88 | HTR3A (0.38) | HTR3ALMNAKMT2AMEN1ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473507-B1 | STABLE SNS-595 COMPOSITIONS AND METHODS OF PREPARATION | SUNESIS PHARMACEUTICALS INC (US) | 2014-03-19 | — | — | EP | disclosed |