Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13089478 | 0.95 | THRB (0.51) | THRBSMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL1072168 | 0.95 | THRB (0.51) | THRBSMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL17279039 | 0.95 | THRB (0.51) | THRBSMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL25501133 | 0.94 | THRB (0.52) | THRBSMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL14280595 | 0.94 | HTT (0.49) | THRBSMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL12510630 | 0.94 | HTT (0.49) | THRBSMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL223268 | 0.94 | HTT (0.49) | THRBSMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL12768610 | 0.94 | HTT (0.49) | THRBSMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL12794263 | 0.94 | HTT (0.49) | THRBSMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL16996738 | 0.93 | HTT (0.44) | THRBSMN1; SMN2NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2325168-B1 | POLYMERIZABLE OPTICALLY ACTIVE IMIDE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND | ADEKA CORP (JP) | 2014-03-19 | — | — | EP | disclosed |