SCHEMBL1072168

SCHEMBL1072168

C=CC(=O)OCCCCCCOc1ccc(CCc2ccc(OC(=O)c3ccc(OCCCCCCOC(=O)C=C)cc3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.51
HTT P42858 3/20 0.48
CYP3A4 P08684 2/20 0.47
ALDH1A1 P00352 2/20 0.47
TSHR P16473 2/20 0.47
NPC1 O15118 3/20 0.47
LMNA P02545 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
NFKB1 P19838 3/20 0.47
NFKB2 Q00653 3/20 0.47
RELA Q04206 3/20 0.47
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
MAPT P10636 5/20 0.43
PRSS1 P07477 1/20 0.43
ACR P10323 1/20 0.43
POLB P06746 2/20 0.42
APEX1 P27695 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13089478 1.00 THRB (0.51) THRBHTTCYP3A4ALDH1A1TSHR
SCHEMBL17279039 1.00 THRB (0.51) THRBHTTCYP3A4ALDH1A1TSHR
SCHEMBL25501133 0.99 THRB (0.52) THRBHTTCYP3A4ALDH1A1TSHR
SCHEMBL12604124 0.96 THRB (0.50) THRBHTTCYP3A4ALDH1A1TSHR
SCHEMBL14000685 0.96 THRB (0.53) THRBHTTCYP3A4ALDH1A1TSHR
SCHEMBL17364495 0.96 THRB (0.53) THRBHTTCYP3A4ALDH1A1TSHR
SCHEMBL26079372 0.95 THRB (0.47) THRBHTTCYP3A4ALDH1A1TSHR
SCHEMBL15580466 0.95 THRB (0.47) THRBHTTCYP3A4ALDH1A1TSHR
SCHEMBL19844483 0.95 THRB (0.47) THRBHTTCYP3A4ALDH1A1TSHR
SCHEMBL17279042 0.94 THRB (0.58) THRBCYP3A4ALDH1A1TSHRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240069264-A1 LAMINATE, REFLECTION PREVENTION SYSTEM, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2024-02-29 US disclosed
US-20230303926-A1 LIQUID CRYSTAL COMPOSITION, LIGHT ABSORPTION ANISOTROPIC LAYER, LAMINATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-09-28 US disclosed
US-20230288751-A1 OPTICAL LAMINATE AND METHOD OF PRODUCING THE OPTICAL LAMINATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-09-14 US disclosed
US-20230265346-A1 LIQUID CRYSTAL COMPOSITION, OPTICALLY ANISOTROPIC LAYER, LAMINATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-08-24 US disclosed
US-20230159827-A1 LIQUID CRYSTAL COMPOSITION, FLUORINE-CONTAINING POLYMER, OPTICALLY ANISOTROPIC LAYER, LAMINATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-05-25 US disclosed
US-20230151275-A1 COMPOUND, COMPOSITION FOR ANISOTROPIC DYE FILMS INCLUDING THE COMPOUND, ANISOTROPIC DYE FILM, AND OPTICAL ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2023-05-18 US disclosed
US-20210108142-A1 POLARIZED LUMINESCENT FILM DIC CORPORATION (JP) 2021-04-15 US disclosed
US-10961456-B2 Dichroic dye compound, polarizing film, and uses thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-03-30 US disclosed
US-10514484-B2 Dichroic dye compound, polarizing film, and uses thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-12-24 US disclosed
US-10023743-B2 Dichroic pigment compounds and compositions containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-07-17 US disclosed
EP-1682930-B1 DICHROIC GUEST-HOST POLARIZER COMPRISING AN ORIENTED POLYMER FILM SUMITOMO CHEMICAL CO (JP) 2011-01-19 EP disclosed
US-20100267858-A1 DICHROIC GUEST-HOST POLARIZER COMPRISING AN ORIENTED POLYMER FILM LUB JOHAN 2010-10-21 US disclosed
US-20100267858-A1 DICHROIC GUEST-HOST POLARIZER COMPRISING AN ORIENTED POLYMER FILM LUB JOHAN 2010-10-21 US disclosed
US-7763330-B2 Dichroic guest-host polarizer comprising an oriented polymer film SUMITOMO CHEMICAL CO., LTD. (JP) 2010-07-27 US disclosed
US-7763330-B2 Dichroic guest-host polarizer comprising an oriented polymer film SUMITOMO CHEMICAL CO., LTD. (JP) 2010-07-27 US disclosed
EP-2159611-A1 Polymerizable liquid crystal and oriented polymer film Sumitomo Chemical Company, Limited (JP) 2010-03-03 EP disclosed
US-20070024970-A1 Dichroic guest-host polarizer comprising an oriented polymer film SUMITOMO CHEMICAL CO., LTD. (JP) 2007-02-01 US disclosed
US-20070024970-A1 Dichroic guest-host polarizer comprising an oriented polymer film SUMITOMO CHEMICAL CO., LTD. (JP) 2007-02-01 US disclosed
EP-1682930-A1 DICHROIC GUEST-HOST POLARIZER COMPRISING AN ORIENTED POLYMER FILM Koninklijke Philips Electronics N.V. (NL) 2006-07-26 EP disclosed
WO-2005045485-A1 DICHROIC GUEST-HOST POLARIZER COMPRISING AN ORIENTED POLYMER FILM KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2005-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267858-A1 DICHROIC GUEST-HOST POLARIZER COMPRISING AN ORIENTED POLYMER FILM ZW10, DSC1, VIM THRB 4357/4885HTT 2512/4885CYP3A4 2060/4885
US-10961456-B2 Dichroic dye compound, polarizing film, and uses thereof CRY1, C5, C9 THRB 3567/4885HTT 3792/4885CYP3A4 171/4885
US-10514484-B2 Dichroic dye compound, polarizing film, and uses thereof CRY1, CHRM1, CRY2 THRB 3293/4885HTT 3481/4885CYP3A4 148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.