Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12794263 | 1.00 | HTT (0.49) | HTTTHRBTSHRCYP3A4ALDH1A1 | |
| SCHEMBL14280595 | 1.00 | HTT (0.49) | HTTTHRBTSHRCYP3A4ALDH1A1 | |
| SCHEMBL12768610 | 1.00 | HTT (0.49) | HTTTHRBTSHRCYP3A4ALDH1A1 | |
| SCHEMBL12510630 | 1.00 | HTT (0.49) | HTTTHRBTSHRCYP3A4ALDH1A1 | |
| SCHEMBL8666203 | 0.99 | THRB (0.50) | HTTTHRBTSHRCYP3A4ALDH1A1 | |
| SCHEMBL22245659 | 0.99 | THRB (0.50) | HTTTHRBTSHRCYP3A4ALDH1A1 | |
| SCHEMBL14370289 | 0.99 | THRB (0.50) | HTTTHRBTSHRCYP3A4ALDH1A1 | |
| SCHEMBL17301297 | 0.99 | THRB (0.50) | HTTTHRBTSHRCYP3A4ALDH1A1 | |
| SCHEMBL711551 | 0.96 | HTT (0.46) | HTTTHRBTSHRCYP3A4ALDH1A1 | |
| SCHEMBL427272 | 0.96 | THRB (0.50) | HTTTHRBTSHRCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3343285-A1 | LIQUID CRYSTAL CELL | LG Chem, Ltd. (KR) | 2018-07-04 | — | — | EP | disclosed |
| EP-2698411-B9 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2017-12-06 | — | — | EP | disclosed |
| EP-2698411-B1 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2017-02-01 | — | — | EP | disclosed |
| EP-2698412-B1 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2016-10-12 | — | — | EP | disclosed |
| CN-102112579-B | Mesogen-containing compounds | TRANSITIONS OPTICAL, INC. (US) | 2014-10-29 | — | — | CN | disclosed |
| EP-2303987-B9 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2014-09-10 | — | — | EP | disclosed |
| EP-2303987-B1 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2014-03-26 | — | — | EP | disclosed |
| EP-2698413-A2 | Mesogen containing compounds | TRANSITIONS OPTICAL, INC. (US) | 2014-02-19 | — | — | EP | disclosed |
| EP-2698412-A2 | Mesogen containing compounds | TRANSITIONS OPTICAL, INC. (US) | 2014-02-19 | — | — | EP | disclosed |
| EP-2698411-A2 | Mesogen containing compounds | TRANSITIONS OPTICAL, INC. (US) | 2014-02-19 | — | — | EP | disclosed |
| US-7910020-B2 | Liquid crystal compositions comprising mesogen containing compounds | TRANSITIONS OPTICAL, INC. (US) | 2011-03-22 | — | — | US | disclosed |
| US-20100014010-A1 | FORMULATIONS COMPRISING MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2010-01-21 | — | — | US | disclosed |
| US-20090326186-A1 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2009-12-31 | — | — | US | disclosed |
| US-20090323011-A1 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2009-12-31 | — | — | US | disclosed |
| US-20090323012-A1 | LIQUID CRYSTAL COMPOSITIONS COMPRISING MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPITCAL, INC. (US) | 2009-12-31 | — | — | US | disclosed |
| WO-2009158483-A1 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2009-12-30 | — | — | WO | disclosed |
| WO-2009158488-A1 | LIQUID CRYSTAL COMPOSITIONS COMPRISING MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2009-12-30 | — | — | WO | disclosed |
| US-6303050-B1 | COMPOUNDS OF A DEFINED STRUCTURE CAN BE USED IN A PLANNED MANNER FOR BUILDING UP LIQUID-CRYSTALLINE POLYMERS AND THUS FOR CONTROLLING THE CHARACTERISTICS OF THESE POLYMERS. | DAIMLERCHRYSLER AG (DE) | 2001-10-16 | — | — | US | disclosed |
| EP-1015525-A1 | DYES WITH OPTICALLY VARIABLE PROPERTIES | Clariant GmbH (DE) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999011734-A1 | DYES WITH OPTICALLY VARIABLE PROPERTIES | CLARIANT GMBH (DE) | 1999-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100014010-A1 | FORMULATIONS COMPRISING MESOGEN CONTAINING COMPOUNDS | MYOC, RARG, MTX2 | HTT 794/4885THRB 3857/4885TSHR 3245/4885 |
| US-20090326186-A1 | MESOGEN CONTAINING COMPOUNDS | MYOC, BMP2, RARG | HTT 1202/4885THRB 3786/4885TSHR 3521/4885 |
| US-20090323011-A1 | MESOGEN CONTAINING COMPOUNDS | MYOC, BMP2, RARG | HTT 1202/4885THRB 3786/4885TSHR 3521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.