Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10249223 | 0.80 | EPHB4 (0.43) | L3MBTL1HSD17B10ADORA2AADORA1LMNA | |
| SCHEMBL4349419 | 0.75 | L3MBTL1 (0.56) | L3MBTL1CREBBPPOLBTDP1HDAC3 | |
| SCHEMBL6264956 | 0.74 | L3MBTL1 (0.65) | L3MBTL1CREBBPPOLBTDP1CYP19A1 | |
| SCHEMBL21536474 | 0.74 | SCD5 (0.44) | L3MBTL1POLBTDP1HDAC3ADORA2A | |
| SCHEMBL2413457 | 0.73 | L3MBTL1 (0.62) | L3MBTL1CREBBPPOLBTDP1HDAC3 | |
| SCHEMBL272966 | 0.73 | L3MBTL1 (0.62) | L3MBTL1CREBBPPOLBTDP1HDAC3 | |
| SCHEMBL14920616 | 0.73 | L3MBTL1 (0.62) | L3MBTL1CREBBPPOLBTDP1HDAC3 | |
| SCHEMBL130830 | 0.73 | L3MBTL1 (0.62) | L3MBTL1CREBBPPOLBTDP1CYP19A1 | |
| SCHEMBL10283891 | 0.73 | L3MBTL1 (0.62) | L3MBTL1CREBBPPOLBTDP1HDAC3 | |
| SCHEMBL950986 | 0.73 | MAPT (0.67) | L3MBTL1CREBBPPOLBTDP1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2294065-B1 | INDOLYL-PYRIDONE DERIVATIVES HAVING CHECKPOINT KINASE 1 INHIBITORY ACTIVITY | VERNALIS R&D LTD (GB) | 2014-03-19 | — | — | EP | disclosed |