Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP12 | P39900 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9344802 | 0.84 | CES2 (0.50) | MMP2MMP9MMP12GRIK1GRIK2 | |
| SCHEMBL28574985 | 0.84 | CES2 (0.50) | MMP2MMP9MMP12GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL928942 | 0.83 | MMP2 (0.49) | MMP2MMP9MMP12GRIK1GRIK2 | |
| SCHEMBL27287213 | 0.82 | CES2 (0.49) | MMP2MMP9MMP12GRIK1GRIK2 | |
| SCHEMBL22151836 | 0.81 | MMP2 (0.50) | MMP2MMP9MMP12GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL9449101 | 0.81 | CES2 (0.47) | MMP2MMP9MMP12GRIK1GRIK2 | |
| SCHEMBL11137673 | 0.81 | ALDH1A1 (0.54) | MMP2MMP9MMP12SPHK1S1PR2 | |
| SCHEMBL11133669 | 0.81 | SPHK1 (0.44) | SPHK1S1PR2S1PR1BDKRB2 | |
| SCHEMBL11262543 | 0.79 | SPHK1 (0.48) | SPHK1S1PR2S1PR1MAPTALDH1A1 | |
| SCHEMBL11134214 | 0.79 | S1PR1 (0.58) | SPHK1S1PR2S1PR1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2105298-B1 | Negative-working lithographic printing plate precursor and method of lithographic printing using same | FUJIFILM CORP (JP) | 2014-03-19 | — | — | EP | disclosed |