Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301030 | 0.83 | ADRA1A (0.54) | DRD3DRD2HTR1ADRD4ADRA1A | |
| SCHEMBL13809540 | 0.78 | ADRA1A (0.53) | DRD3DRD2HTR1AHTR2ADRD4 | |
| SCHEMBL13809829 | 0.78 | KDM4E (0.39) | HTR2ADRD4ADRA1ALMNAMAPT | |
| SCHEMBL4303438 | 0.78 | KDM4E (0.39) | HTR2ADRD4ADRA1ALMNAMAPT | |
| SCHEMBL2955859 | 0.78 | ADRA1A (0.38) | HTR1AHTR2ADRD4ADRA1AMAPT | |
| SCHEMBL2955868 | 0.78 | ADRA1A (0.38) | HTR1AHTR2ADRD4ADRA1AMAPT | |
| SCHEMBL2957077 | 0.78 | ADRA1A (0.38) | HTR1AHTR2ADRD4ADRA1AMAPT | |
| SCHEMBL2955865 | 0.78 | ADRA1A (0.38) | HTR1AHTR2ADRD4ADRA1AMAPT | |
| SCHEMBL2957073 | 0.78 | ADRA1A (0.38) | HTR1AHTR2ADRD4ADRA1AMAPT | |
| SCHEMBL4308612 | 0.76 | KDM4E (0.39) | HTR2AHTR2CDRD4ADRA1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9340489-B2 | Process for the preparation of deuterated compounds containing N-alkyl groups | SANOFI (FR) | 2016-05-17 | — | — | US | disclosed |
| US-20140081019-A1 | PROCESS FOR THE PREPARATION OF DEUTERATED COMPOUNDS CONTAINING N-ALKYL GROUPS | SANOFI (FR) | 2014-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140081019-A1 | PROCESS FOR THE PREPARATION OF DEUTERATED COMPOUNDS CONTAINING N-ALKYL GROUPS | HDHD5, DRD4, DRD2 | ALDH1A1 3944/4885DRD3 6/4885DRD2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.