SCHEMBL15599290

SCHEMBL15599290

Cc1cnc(-c2ccc(-c3cnc(C)cn3)cc2)cn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.43
CCR1 P32246 1/20 0.40
CCR5 P51681 1/20 0.40
CCR8 P51685 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
KDM1A O60341 1/20 0.39
P2RX7 Q99572 1/20 0.37
HSD17B1 P14061 1/20 0.37
HSD17B2 P37059 1/20 0.37
HPGDS O60760 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP1A2 P05177 2/20 0.36
ALDH1A1 P00352 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CLK4 Q9HAZ1 1/20 0.36
METAP2 P50579 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10000240 0.93 KDM1A (0.47) ABL1CCR1CCR5CCR8HDAC6
SCHEMBL17051511 0.91 KDM1A (0.46) ABL1CCR1CCR5CCR8HDAC6
SCHEMBL17051555 0.91 KDM1A (0.46) ABL1CCR1CCR5CCR8HDAC6
SCHEMBL2614945 0.89 NPC1 (0.47) ABL1KDM1AP2RX7MEN1KMT2A
SCHEMBL30497728 0.89 KEAP1 (0.42) ABL1KDM1AMEN1KMT2ATDP1
SCHEMBL10165350 0.89 MAPK1 (0.46) ABL1ALDH1A1NPC1RAB9APDGFRB
SCHEMBL17055548 0.89 MEN1 (0.49) MEN1KMT2ATDP1HSD17B10NPC1
SCHEMBL17051527 0.89 HPGDS (0.43) ABL1KDM1AHPGDSMEN1KMT2A
SCHEMBL15784437 0.88 HPGDS (0.46) ABL1HDAC6P2RX7HPGDSMEN1
SCHEMBL2716273 0.88 RAB9A (0.48) HDAC6HSD17B1HSD17B2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10038143-B2 Polymer compound, material for electronic elements, material for organic electroluminescent elements, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-07-31 US disclosed
EP-2847809-B1 OLIGOMERIC ORGANIC LIGHT EMITTING DIODE(OLED)MATERIALS CONTAINING MULTIPLE CROSSLINKING FUNCTIONS LOMOX LTD (GB) 2017-12-20 EP disclosed
US-9761804-B2 Oligomeric organic light emitting diode (OLED) materials containing multiple crosslinking functions LOMOX LIMITED (GB) 2017-09-12 US disclosed
US-20150249215-A1 POLYMER COMPOUND, MATERIAL FOR ELECTRONIC ELEMENTS, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-09-03 US disclosed
WO-2013167857-A1 OLIGOMERIC ORGANIC LIGHT EMITTING DIODE(OLED)MATERIALS CONTAINING MULTIPLE CROSSLINKING FUNCTIONS LOMOX LIMITED (GB) 2013-11-14 WO disclosed