Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 17/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15486750 | 0.82 | PTGDR2 (0.53) | PTGDR2AKR1B1CYP2C9KDM4EPOLB | |
| SCHEMBL15733080 | 0.80 | MARK4 (0.57) | PTGDR2AKR1B1CYP2C9KDM4EPOLB | |
| SCHEMBL16709583 | 0.78 | PTGDR2 (0.50) | PTGDR2AKR1B1CYP2C9KDM4EPOLB | |
| SCHEMBL19368919 | 0.78 | PTGDR2 (0.63) | PTGDR2AKR1B1CYP2C9PTGS1SLC6A4 | |
| SCHEMBL21027245 | 0.77 | GLA (0.74) | PTGDR2AKR1B1KDM4E | |
| SCHEMBL16709584 | 0.76 | PTGDR2 (0.51) | PTGDR2AKR1B1CYP2C9KDM4EPOLB | |
| SCHEMBL16156848 | 0.74 | KDM4E (0.73) | PTGDR2AKR1B1CYP2C9KDM4EPOLB | |
| SCHEMBL13957020 | 0.74 | RORA (0.37) | PTGDR2AKR1B1CYP2C9KDM4EPOLB | |
| SCHEMBL21027001 | 0.73 | GLA (0.60) | PTGDR2AKR1B1CYP2C9KDM4EPOLB | |
| SCHEMBL16923533 | 0.71 | DNM1 (0.45) | CYP2C9KDM4EHSD17B10CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014031986-A1 | PRO-NEUROGENIC COMPOUNDS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-02-27 | — | — | WO | disclosed |