Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 16/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15486120 | 0.83 | TSPO (0.45) | PTGDR2AKR1B1ALDH1A1MAPK1STAT3 | |
| SCHEMBL1406080 | 0.80 | PTGDR2 (0.75) | PTGDR2AKR1B1ALDH1A1MAPK1STAT3 | |
| SCHEMBL1386238 | 0.79 | PTGDR2 (0.74) | PTGDR2AKR1B1ALDH1A1MAPK1STAT3 | |
| SCHEMBL15486750 | 0.78 | PTGDR2 (0.53) | PTGDR2AKR1B1CYP2C9KDM4EPOLB | |
| SCHEMBL15599705 | 0.78 | PTGDR2 (0.53) | PTGDR2AKR1B1CYP2C9KDM4EPOLB | |
| SCHEMBL15733080 | 0.77 | MARK4 (0.57) | PTGDR2AKR1B1CYP2C9KDM4EPOLB | |
| SCHEMBL20046019 | 0.76 | RORA (0.56) | ALDH1A1 | |
| SCHEMBL8029433 | 0.76 | NTRK1 (0.46) | ALDH1A1MAPK1STAT3KDM4EL3MBTL1 | |
| SCHEMBL18055752 | 0.76 | ALDH1A1 (0.47) | ALDH1A1MAPK1KDM4E | |
| SCHEMBL19368919 | 0.75 | PTGDR2 (0.63) | PTGDR2AKR1B1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015070237-A1 | NEUROPROTECTIVE CHEMICALS AND METHODS FOR IDENTIFYING AND USING SAME | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-05-14 | — | — | WO | disclosed |