Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.49 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2811831 | 1.00 | GBA1 (0.49) | GBA1FUCA1S1PR5LMNAHRH4 | |
| SCHEMBL17005370 | 1.00 | GBA1 (0.49) | GBA1FUCA1S1PR5LMNAHRH4 | |
| SCHEMBL11392608 | 1.00 | GBA1 (0.49) | GBA1FUCA1S1PR5LMNAHRH4 | |
| SCHEMBL17005417 | 0.84 | GBA1 (0.47) | GBA1FUCA1S1PR5DRD2DRD4 | |
| SCHEMBL17065392 | 0.84 | S1PR5 (0.49) | FUCA1S1PR5LMNAHRH3 | |
| SCHEMBL11384891 | 0.83 | L3MBTL1 (0.51) | GBA1LMNAHRH4HRH3 | |
| SCHEMBL17005427 | 0.82 | LMNA (0.46) | LMNAHRH4HRH3 | |
| SCHEMBL2806983 | 0.82 | LMNA (0.46) | LMNAHRH4HRH3 | |
| SCHEMBL3128357 | 0.82 | LMNA (0.46) | LMNAHRH4HRH3 | |
| SCHEMBL8305056 | 0.82 | LMNA (0.50) | LMNAHRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014042263-A1 | NOVEL RENIN INHIBITOR | 田辺三菱製薬株式会社 (JP) | 2014-03-20 | — | — | WO | disclosed |