Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 15/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15565364 | 0.89 | ENPP2 (0.48) | ENPP2LPAR1AKR1B10AKR1A1AKR1B1 | |
| SCHEMBL15599971 | 0.89 | ENPP2 (0.48) | ENPP2LPAR1AKR1B10AKR1A1AKR1B1 | |
| SCHEMBL15599984 | 0.85 | ENPP2 (0.43) | ENPP2LPAR1 | |
| SCHEMBL20403951 | 0.84 | ENPP2 (0.45) | ENPP2LPAR1S1PR5 | |
| SCHEMBL15600021 | 0.83 | ENPP2 (0.48) | ENPP2LPAR1EPHX2S1PR5 | |
| SCHEMBL15564597 | 0.83 | ENPP2 (0.48) | ENPP2LPAR1EPHX2S1PR5 | |
| SCHEMBL15599979 | 0.83 | ENPP2 (0.49) | ENPP2LPAR1AKR1B10AKR1A1AKR1B1 | |
| SCHEMBL20403997 | 0.83 | ENPP2 (0.49) | ENPP2LPAR1AKR1B10AKR1A1AKR1B1 | |
| SCHEMBL20403979 | 0.82 | ENPP2 (0.52) | ENPP2LPAR1S1PR5 | |
| SCHEMBL15599983 | 0.82 | ENPP2 (0.57) | ENPP2LPAR1AKR1B10AKR1A1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014025709-A1 | COMPOUNDS THAT ARE S1P MODULATING AGENTS AND/OR ATX MODULATING AGENTS | BIOGEN IDEC MA INC. (US) | 2014-02-13 | — | — | WO | disclosed |