Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 10/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15599971 | 0.86 | ENPP2 (0.48) | ENPP2LPAR1GRM2 | |
| SCHEMBL15565364 | 0.86 | ENPP2 (0.48) | ENPP2LPAR1GRM2 | |
| SCHEMBL15599982 | 0.85 | ENPP2 (0.47) | ENPP2LPAR1 | |
| SCHEMBL20403979 | 0.80 | ENPP2 (0.52) | ENPP2LPAR1GRM2 | |
| SCHEMBL20403951 | 0.79 | ENPP2 (0.45) | ENPP2LPAR1 | |
| SCHEMBL15599983 | 0.77 | ENPP2 (0.57) | ENPP2LPAR1 | |
| SCHEMBL15565622 | 0.77 | ENPP2 (0.57) | ENPP2LPAR1 | |
| SCHEMBL15565300 | 0.76 | ENPP2 (0.46) | ENPP2LPAR1 | |
| SCHEMBL15565297 | 0.76 | ENPP2 (0.46) | ENPP2LPAR1 | |
| SCHEMBL15599979 | 0.76 | ENPP2 (0.49) | ENPP2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014025709-A1 | COMPOUNDS THAT ARE S1P MODULATING AGENTS AND/OR ATX MODULATING AGENTS | BIOGEN IDEC MA INC. (US) | 2014-02-13 | — | — | WO | disclosed |