Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15610552 | 1.00 | TDP1 (0.51) | TDP1L3MBTL1GLASMN1; SMN2HDAC4 | |
| SCHEMBL15610551 | 1.00 | TDP1 (0.51) | TDP1L3MBTL1GLASMN1; SMN2HDAC4 | |
| SCHEMBL15610148 | 0.90 | SMN1; SMN2 (0.48) | TDP1L3MBTL1GLASMN1; SMN2HDAC4 | |
| SCHEMBL15610147 | 0.90 | SMN1; SMN2 (0.48) | TDP1L3MBTL1GLASMN1; SMN2HDAC4 | |
| SCHEMBL15610437 | 0.90 | SMN1; SMN2 (0.48) | TDP1L3MBTL1GLASMN1; SMN2HDAC4 | |
| SCHEMBL513385 | 0.83 | ALDH1A1 (0.61) | TDP1GLASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL7475644 | 0.81 | GLA (0.53) | GLASMN1; SMN2ALDH1A1POLBCYP1A2 | |
| SCHEMBL7475632 | 0.81 | GLA (0.53) | GLASMN1; SMN2ALDH1A1POLBCYP1A2 | |
| SCHEMBL11600935 | 0.79 | CA1 (0.48) | TDP1L3MBTL1HDAC4HDAC7HDAC8 | |
| SCHEMBL5906135 | 0.78 | POLB (0.55) | TDP1L3MBTL1GLASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900629-A2 | F-18 RADIOLABELED COMPOUNDS FOR DIAGNOSING AND MONITORING KIDNEY FUNCTION | Kasina Laila Innova Pharmaceuticals Private Ltd. (IN) | 2015-08-05 | — | — | EP | disclosed |
| US-8906344-B2 | F-18 radiolabeled compounds for diagnosing and monitoring kidney function | KASINA LAILA INNOVA PHARMACEUTICALS PRIVATE LIMITED (IN) | 2014-12-09 | — | — | US | disclosed |
| US-20140086837-A1 | F-18 RADIOLABELED COMPOUNDS FOR DIAGNOSING AND MONITORING KIDNEY FUNCTION | KASINA LAILA INNOVA PHARMACEUTICALS PRIVATE LIMITED (IN) | 2014-03-27 | — | — | US | disclosed |
| WO-2014045306-A2 | F-18 RADIOLABELED COMPOUNDS FOR DIAGNOSING AND MONITORING KIDNEY FUNCTION | KASINA LAILA INNOVA PHARMACEUTICALS PRIVATE LIMITED (IN) | 2014-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140086837-A1 | F-18 RADIOLABELED COMPOUNDS FOR DIAGNOSING AND MONITORING KIDNEY FUNCTION | SLCO1B1, SLCO1B3, SLCO2B1 | TDP1 4647/4885L3MBTL1 4725/4885GLA 1013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.