Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.67 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11360607 | 0.90 | SIGMAR1 (0.85) | SIGMAR1ALDH1A1KDM4ERAB9APLA2G1B | |
| SCHEMBL1852774 | 0.85 | SIGMAR1 (0.71) | SIGMAR1ALDH1A1KDM4ERAB9APLA2G1B | |
| SCHEMBL16256924 | 0.83 | KDM4E (0.68) | SIGMAR1ALDH1A1KDM4ERAB9APLA2G1B | |
| SCHEMBL9417737 | 0.82 | SIGMAR1 (0.72) | SIGMAR1ALDH1A1KDM4ERAB9APLA2G1B | |
| SCHEMBL23851311 | 0.82 | SIGMAR1 (0.72) | SIGMAR1ALDH1A1KDM4ERAB9APLA2G1B | |
| SCHEMBL18938500 | 0.82 | SIGMAR1 (0.67) | SIGMAR1ALDH1A1KDM4ERAB9APLA2G1B | |
| SCHEMBL13779315 | 0.82 | KMT2A (0.69) | SIGMAR1ALDH1A1KDM4ERAB9APLA2G1B | |
| SCHEMBL20353642 | 0.81 | SIGMAR1 (0.71) | SIGMAR1ALDH1A1KDM4ERAB9APLA2G1B | |
| Hydrochloric Acid SCHEMBL11467058 | 0.81 | SIGMAR1 (0.70) | SIGMAR1ALDH1A1KDM4ERAB9APLA2G1B | |
| SCHEMBL3210628 | 0.81 | ALDH1A1 (0.73) | SIGMAR1ALDH1A1KDM4ERAB9APLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170158702-A1 | MULTIVALENT RAS BINDING COMPOUNDS | KYRAS THERAPEUTICS, INC. | 2017-06-08 | — | — | US | disclosed |
| US-20140088069-A1 | NOVEL ANTIBACTERIAL COMBINATION THERAPY | MCMASTER UNIVERSITY (CA) | 2014-03-27 | — | — | US | disclosed |
| US-20140088069-A1 | NOVEL ANTIBACTERIAL COMBINATION THERAPY | MCMASTER UNIVERSITY (CA) | 2014-03-27 | — | — | US | disclosed |
| US-20140088069-A1 | NOVEL ANTIBACTERIAL COMBINATION THERAPY | MCMASTER UNIVERSITY (CA) | 2014-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158702-A1 | MULTIVALENT RAS BINDING COMPOUNDS | KRAS, HRAS, NRAS | SIGMAR1 3734/4885ALDH1A1 4640/4885KDM4E 3955/4885 |
| US-20140088069-A1 | NOVEL ANTIBACTERIAL COMBINATION THERAPY | NCBP2, TPX2, GTPBP4 | SIGMAR1 1220/4885ALDH1A1 4803/4885KDM4E 4184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.