SCHEMBL1561083

SCHEMBL1561083

C=Cc1ccccc1CNC(C)N[CH]CC

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 3/20 0.33
ADRB1 P08588 3/20 0.33
LMNA P02545 3/20 0.33
HTR1A P08908 1/20 0.33
ADRB3 P13945 1/20 0.33
ADRA2C P18825 1/20 0.33
SLC6A2 P23975 1/20 0.33
BDKRB2 P30411 1/20 0.33
SLC6A4 P31645 1/20 0.33
ADRA1A P35348 1/20 0.33
HTR2B P41595 1/20 0.33
KCNH2 Q12809 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
TSHR P16473 1/20 0.33
NFKB1 P19838 1/20 0.33
KDM4E B2RXH2 2/20 0.33
PMP22 Q01453 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19876841 0.81 BCHE (0.35) ADRB2ADRB1LMNAHTR1AADRB3
SCHEMBL10989194 0.81 LMNA (0.38) ADRB2ADRB1LMNAHTR1AADRB3
SCHEMBL10629904 0.79 BCHE (0.44) ADRB2ADRB1LMNAHTR1AADRB3
SCHEMBL896935 0.77 ADRB2 (0.30) ADRB2ADRB1LMNAHTR1AADRB3
SCHEMBL1560778 0.74 SIGMAR1 (0.50) LMNAKDM4EPOLBMAPK1ALDH1A1
Isopropylhydroxylamine SCHEMBL11030645 0.73 ADRB2 (0.37) ADRB2ADRB1LMNAHTR1AADRB3
SCHEMBL8780180 0.73 LMNA (0.38) ADRB2ADRB1LMNAHTR1AADRB3
SCHEMBL6566162 0.72 POLB (0.42) KDM4EPOLBALDH1A1
SCHEMBL145171 0.72
SCHEMBL14696221 0.72 ADRB2 (0.32) ADRB2ADRB1LMNAHTR1AADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10588222-B2 Coating metal foil with n-heterocyclic carbene compounds containing organic functionalities for improving metal-to-resin adhesion INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2020-03-10 US disclosed
US-20200053886-A1 COATING METAL FOIL WITH N-HETEROCYCLIC CARBENE COMPOUNDS CONTAINING ORGANIC FUNCTIONALITIES FOR IMPROVING METAL-TO-RESIN ADHESION INTERNATIONAL BUSINESS MACHINES CORPORATION 2020-02-13 US disclosed
US-10506723-B2 Enhanced substrate includes a carbene-coated metal foil laminated to a substrate that includes glass fiber impregnated with a base polymer INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2019-12-10 US disclosed
US-10093764-B2 Block copolymers in laminate manufacturing INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-10-09 US disclosed
US-20180168051-A1 COATING METAL FOIL WITH N-HETEROCYCLIC CARBENE COMPOUNDS CONTAINING ORGANIC FUNCTIONALITIES FOR IMPROVING METAL-TO-RESIN ADHESION INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-06-14 US disclosed
US-9974193-B2 Coating metal foil with N-heterocyclic carbene compounds containing organic functionalities for improving metal-to-resin adhesion INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-15 US disclosed
US-9879110-B2 Block copolymers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-01-30 US disclosed
US-20160157361-A1 COATING METAL FOIL WITH N-HETEROCYCLIC CARBENE COMPOUNDS CONTAINING ORGANIC FUNCTIONALITIES FOR IMPROVING METAL-TO-RESIN ADHESION INTERNATIONAL BUSINESS MACHINES CORPORATION 2016-06-02 US disclosed
US-20160157362-A1 COATING METAL FOIL WITH N-HETEROCYCLIC CARBENE COMPOUNDS CONTAINING ORGANIC FUNCTIONALITIES FOR IMPROVING METAL-TO-RESIN ADHESION INTERNATIONAL BUSINESS MACHINES CORPORATION 2016-06-02 US disclosed
US-20160145400-A1 BLOCK COPOLYMERS IN LAMINATE MANUFACTURING INTERNATIONAL BUSINESS MACHINES CORPORATION 2016-05-26 US disclosed
US-20160145371-A1 BLOCK COPOLYMERS IN LAMINATE MANUFACTURING INTERNATIONAL BUSINESS MACHINES CORPORATION 2016-05-26 US disclosed
US-9351405-B2 Hydrophobic silane coating for preventing conductive anodic filament (CAF) growth in printed circuit boards INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2016-05-24 US disclosed
EP-2303896-B1 SILANE COUPLING AGENTS FOR PRINTED CIRCUIT BOARDS IBM (US) 2013-11-06 EP disclosed
US-20130280417-A1 Hydrophobic Silane Coating for Preventing Conductive Anodic Filament (CAF) Growth in Printed Circuit Boards INTERNATIONAL BUSINESS MACHINES CORPORATION 2013-10-24 US disclosed
WO-2011107418-A1 HYDROPHOBIC SILANE COATING FOR PREVENTING CONDUCTIVE ANODIC FILAMENT (CAF) GROWTH IN PRINTED CIRCUIT BOARDS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-09-09 WO disclosed
US-20110214909-A1 Hydrophobic Silane Coating for Preventing Conductive Anodic Filament (CAF) Growth in Printed Circuit Boards INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-09-08 US disclosed
EP-2303896-A1 SILANE COUPLING AGENTS FOR PRINTED CIRCUIT BOARDS International Business Machines Corporation (US) 2011-04-06 EP disclosed
WO-2010097261-A1 SILANE COUPLING AGENTS FOR PRINTED CIRCUIT BOARDS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-09-02 WO disclosed
US-20100212944-A1 Silane Coupling Agents for Printed Circuit Boards INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-08-26 US disclosed
US-20100193745-A1 CONDUCTIVE POLYMER FILM, CONDUCTIVE POLYMERIC MATERIAL AND ELECTRONIC DEVICE SANYO ELECTRIC CO., LTD. (JP) 2010-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100212944-A1 Silane Coupling Agents for Printed Circuit Boards ABL2, HCK, SRC ADRB2 784/4885ADRB1 707/4885LMNA 4374/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.