Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | TEK | Q02763 | 1/20 | 0.52 |
| ▸ | BTK | Q06187 | 10/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.50 |
| ▸ | PRKDC | P78527 | 3/20 | 0.50 |
| ▸ | NUDT14 | O95848 | 2/20 | 0.50 |
| ▸ | NUDT5 | Q9UKK9 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL200349 | 0.89 | NUDT14 (0.62) | LCKKDRTEKBTKPIK3CD | |
| SCHEMBL14617841 | 0.88 | BTK (0.52) | LCKKDRTEKBTKPIK3CD | |
| Hydrochloric Acid SCHEMBL29439185 | 0.87 | NUDT14 (0.61) | LCKKDRTEKBTKPIK3CD | |
| SCHEMBL30387716 | 0.85 | PIK3CD (0.65) | LCKKDRTEKBTKPIK3CD | |
| SCHEMBL15613541 | 0.83 | BTK (0.60) | KDRBTKPIK3CDPIK3CAPIK3CB | |
| SCHEMBL17626654 | 0.82 | NUDT14 (0.48) | LCKBTKPIK3CDPIK3CAPIK3CB | |
| SCHEMBL12808147 | 0.82 | BTK (0.50) | LCKKDRTEKBTKPIK3CD | |
| SCHEMBL18235468 | 0.82 | KDR (0.49) | LCKKDRTEKPIK3CDPIK3CA | |
| SCHEMBL12713498 | 0.82 | PIK3CD (0.50) | LCKKDRTEKBTKPIK3CD | |
| SCHEMBL30387156 | 0.82 | PIK3CD (0.59) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013177668-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE, INC. (CA) | 2013-12-05 | — | — | WO | disclosed |