SCHEMBL15615643

SCHEMBL15615643

CC(C)(C)OC(=O)n1ccc2sccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.41
BUB1 O43683 1/20 0.41
PIK3CD O00329 2/20 0.36
ABL1 P00519 2/20 0.36
EGFR P00533 2/20 0.36
HCK P08631 2/20 0.36
SRC P12931 2/20 0.36
KDR P35968 2/20 0.36
PIK3CA P42336 2/20 0.36
PIK3CB P42338 2/20 0.36
MTOR P42345 2/20 0.36
PIK3CG P48736 2/20 0.36
EPHB4 P54760 2/20 0.36
PRKDC P78527 2/20 0.36
PI4KB Q9UBF8 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34
GPR119 Q8TDV5 2/20 0.34
HTR6 P50406 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL400481 0.75 BCHE (0.41) BCHEBUB1PIK3CDABL1EGFR
SCHEMBL14862397 0.75 HSP90AA1 (0.40) BCHEBUB1PIK3CDABL1EGFR
SCHEMBL31519217 0.74 POLB (0.38) L3MBTL1CCR9HSD17B10POLBTSHR
SCHEMBL691666 0.71 NOTUM (0.59) BCHEBUB1PIK3CDABL1EGFR
SCHEMBL29701136 0.71 NOTUM (0.59) BCHEBUB1PIK3CDABL1EGFR
SCHEMBL20096773 0.71 HSP90AA1 (0.44) BCHEBUB1PIK3CDABL1EGFR
SCHEMBL28935614 0.71 L3MBTL1 (0.46) BCHEBUB1L3MBTL1HTR6FEN1
SCHEMBL31568870 0.71 BUB1 (0.36) BCHEBUB1PIK3CDABL1EGFR
SCHEMBL31321439 0.71 CCR9 (0.49) L3MBTL1CCR9HSD17B10POLBTSHR
SCHEMBL28085950 0.70 NOTUM (0.57) BCHEBUB1PIK3CDABL1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025087365-A1 METTL3 INHIBITOR 杭州邦顺制药有限公司 2025-05-01 WO disclosed
CN-119899188-A METTL3 inhibitors 杭州邦顺制药有限公司 2025-04-29 CN disclosed
WO-2014041518-A1 THIENOPYRROLE DERIVATIVES AS ITK INHIBITORS GLENMARK PHARMACEUTICALS S.A. (CH) 2014-03-20 WO disclosed