Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP51A1 | Q16850 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 2/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15617806 | 1.00 | CYP51A1 (0.46) | CYP51A1CA1CA2CA5ACA9 | |
| SCHEMBL30874461 | 0.81 | CYP51A1 (0.49) | CYP51A1CA1CA2CA5ACA9 | |
| SCHEMBL15590856 | 0.81 | CYP51A1 (0.49) | CYP51A1CA1CA2CA5ACA9 | |
| SCHEMBL16748959 | 0.80 | CA1 (0.58) | CYP51A1CA1CA2CA5ACA9 | |
| SCHEMBL23623817 | 0.77 | CYP51A1 (0.50) | CYP51A1CA1CA2CA5ACA9 | |
| SCHEMBL16242461 | 0.77 | CA1 (0.48) | CYP51A1CA1CA2CA5ACA9 | |
| SCHEMBL13455265 | 0.77 | PLAU (0.47) | CYP51A1CA1CA2CA5ACA9 | |
| SCHEMBL20553240 | 0.77 | CA1 (0.48) | CYP51A1CA1CA2CA5ACA9 | |
| SCHEMBL13449507 | 0.77 | TP53 (0.48) | CYP51A1CA1CA2CA5ACA9 | |
| SCHEMBL14190008 | 0.77 | CYP51A1 (0.46) | CYP51A1CA1CA2CA5ACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105985406-B | A kind of18F-labeled polypeptide compound and preparation method and application thereof | 中国科学院上海应用物理研究所 | 2020-10-23 | — | — | CN | disclosed |
| US-8680260-B2 | 18F-labeled azide compound, reagent for 18F-labeling and method for 18F-labeling of alkyne compound using same | RIKEN (JP) | 2014-03-25 | — | — | US | disclosed |
| US-8680260-B2 | 18F-labeled azide compound, reagent for 18F-labeling and method for 18F-labeling of alkyne compound using same | RIKEN (JP) | 2014-03-25 | — | — | US | disclosed |
| EP-2500338-A1 | F-LABELED AZIDE COMPOUND, REAGENT FOR 18F-LABELING AND METHOD FOR 18F-LABELING OF ALKYNE COMPOUND USING SAME | Riken (JP) | 2012-09-19 | — | — | EP | disclosed |
| US-20120101266-A1 | 18F-LABELED AZIDE COMPOUND, REAGENT FOR 18F-LABELING AND METHOD FOR 18F-LABELING OF ALKYNE COMPOUND USING SAME | RIKEN (JP) | 2012-04-26 | — | — | US | disclosed |
| US-20120101266-A1 | 18F-LABELED AZIDE COMPOUND, REAGENT FOR 18F-LABELING AND METHOD FOR 18F-LABELING OF ALKYNE COMPOUND USING SAME | RIKEN (JP) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101266-A1 | 18F-LABELED AZIDE COMPOUND, REAGENT FOR 18F-LABELING AND METHOD FOR 18F-LABELING OF ALKYNE COMPOUND USING SAME | UMPS, APOBEC3G, FPR1 | CYP51A1 2738/4885CA1 2091/4885CA2 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.