Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15290259 | 0.83 | PTGS2 (0.44) | PTGS2CYP51A1TP53CA1CA2 | |
| SCHEMBL15590856 | 0.81 | CYP51A1 (0.49) | PTGS2CYP51A1TP53CA1CA2 | |
| SCHEMBL30874461 | 0.81 | CYP51A1 (0.49) | PTGS2CYP51A1TP53CA1CA2 | |
| SCHEMBL16748959 | 0.80 | CA1 (0.58) | PTGS2CYP51A1TP53CA1CA2 | |
| SCHEMBL14394949 | 0.79 | CYP3A4 (0.49) | PTGS2CYP51A1TP53CA1CA2 | |
| SCHEMBL16479570 | 0.78 | CYP3A4 (0.49) | PTGS2TP53CA2CYP2C9LPL | |
| SCHEMBL26048600 | 0.78 | PTGS2 (0.41) | PTGS2CYP51A1TP53CA1CA2 | |
| SCHEMBL23623817 | 0.77 | CYP51A1 (0.50) | PTGS2CYP51A1TP53CA1CA2 | |
| SCHEMBL13449507 | 0.77 | TP53 (0.48) | PTGS2CYP51A1TP53CA1CA2 | |
| SCHEMBL19145450 | 0.77 | CYP51A1 (0.46) | PTGS2CYP51A1TP53CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283678-A | Preparation method of C-fluoroalkyl substituted amidine compound and application of C-fluoroalkyl substituted amidine compound in resisting fungal diseases | 中国农业大学 | 2023-06-23 | — | — | CN | claimed |
| CN-113527332-B | Biological activity-possessed caspovir derivative, and preparation method and application thereof | 南开大学 | 2022-07-26 | — | — | CN | claimed |
| CN-113527332-A | Kabauvir derivative with biological activity and preparation method and application thereof | 南开大学 | 2021-10-22 | — | — | CN | claimed |
| CN-113527333-A | Dolutegravir derivative with biological activity and preparation method and application thereof | 南开大学 | 2021-10-22 | — | — | CN | claimed |
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | Atea Pharmaceuticals, Inc. (US) | 2023-10-19 | — | — | US | disclosed |
| CN-116789611-A | Synthetic method of selectively deuterated marked 1,2, 3-triazole | 海南师范大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-116751172-A | Synthesis method of diiodinated 1,2, 3-triazole compound | 海南师范大学 | 2023-09-15 | — | — | CN | disclosed |
| CN-113061138-B | Triazole [5,4-d ] pyrimidinone tricyclic compound, and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2023-05-05 | — | — | CN | disclosed |
| CN-113999211-B | Indazole skeleton derivative containing 1,2,3-triazole with specific activity of resisting prostate cancer | 郑州大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-113527333-B | Dolutegravir derivative with biological activity and preparation method and application thereof | 南开大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-113527332-B | Biological activity-possessed caspovir derivative, and preparation method and application thereof | 南开大学 | 2022-07-26 | — | — | CN | disclosed |
| US-11173480-B2 | Catalyst in which metal is carried on inorganic porous body having hierarchical porous structure, and method for manufacturing said catalyst | SNG INC. (JP) | 2021-11-16 | — | — | US | disclosed |
| US-20080269203-A1 | COMPOSITIONS AND METHODS RELATING TO NOVEL COMPOUNDS AND TARGETS THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-10-30 | — | — | US | disclosed |
| US-20080221303-A1 | Method for the Preparation of Peptide-Oligonucleotide Conjugates | FRUTAROM LTD. (IL) | 2008-09-11 | — | — | US | disclosed |
| US-20070299059-A1 | Compostions and methods relating to novel compounds and targets thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-12-27 | — | — | US | disclosed |
| US-7276348-B2 | Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2007-10-02 | — | — | US | disclosed |
| US-20070135418-A1 | Compositions and methods relating to novel compounds and targets thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-06-14 | — | — | US | disclosed |
| US-20070043033-A1 | Unsolvated benzodiazepine compositions and methods | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2007-02-22 | — | — | US | disclosed |
| CN-1825206-A | Negative resist composition and patterning process | SHINETSU CHEMICAL CO (JP) | 2006-08-30 | — | — | CN | disclosed |
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135418-A1 | Compositions and methods relating to novel compounds and targets thereof | BAX, BAD, GABRB3 | PLAU 4712/4885PTGS2 922/4885CYP51A1 555/4885 |
| US-20070299059-A1 | Compostions and methods relating to novel compounds and targets thereof | CASP1, BAX, BAD | PLAU 4120/4885PTGS2 971/4885CYP51A1 159/4885 |
| US-11173480-B2 | Catalyst in which metal is carried on inorganic porous body having hierarchical porous structure, and method for manufacturing said catalyst | TMEM63A, PORCN, PIEZO1 | PLAU 2598/4885PTGS2 1785/4885CYP51A1 1385/4885 |
| US-20080221303-A1 | Method for the Preparation of Peptide-Oligonucleotide Conjugates | VIP, PTMS, SSTR4 | PLAU 1146/4885PTGS2 4705/4885CYP51A1 3261/4885 |
| US-20070043033-A1 | Unsolvated benzodiazepine compositions and methods | GABRA5, GABRA3, GABRA6 | PLAU 4271/4885PTGS2 2624/4885CYP51A1 268/4885 |
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | NUDT1, PNP, ATIC | PLAU 2323/4885PTGS2 3358/4885CYP51A1 2608/4885 |
| US-20080269203-A1 | COMPOSITIONS AND METHODS RELATING TO NOVEL COMPOUNDS AND TARGETS THEREOF | BAX, BAD, GABRB3 | PLAU 4712/4885PTGS2 922/4885CYP51A1 555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.