Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 1.00 |
| ▸ | CA6 | P23280 | 5/20 | 1.00 |
| ▸ | CA7 | P43166 | 5/20 | 1.00 |
| ▸ | CA9 | Q16790 | 5/20 | 1.00 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 1.00 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 1.00 |
| ▸ | CA2 | P00918 | 4/20 | 1.00 |
| ▸ | CA4 | P22748 | 4/20 | 1.00 |
| ▸ | CA5A | P35218 | 4/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | CA3 | P07451 | 3/20 | 1.00 |
| ▸ | F13A1 | P00488 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | THPO | P40225 | 2/20 | 1.00 |
| ▸ | CA1 | P00915 | 2/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | MTOR | P42345 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 0.93 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3165201 | 1.00 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| Spermidine SCHEMBL8073115 | 1.00 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| Spermidine SCHEMBL288987 | 1.00 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| SCHEMBL3175232 | 1.00 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| Spermine SCHEMBL431884 | 1.00 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| Spermine SCHEMBL5802297 | 1.00 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| Spermidine SCHEMBL15618 | 1.00 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| Spermidine SCHEMBL6253721 | 1.00 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| SCHEMBL4861043 | 0.97 | CA12 (0.93) | CA12CA6CA7CA9CA14 | |
| Spermidine SCHEMBL573651 | 0.97 | LMNA (1.00) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635905-A2 | EFFICIENT AND EFFECTIVE SUPPLEMENT SCREENING FOR THE DEVELOPMENT OF CHEMICALLY DEFINED MEDIA IN CELL CULTURE | AbbVie Inc. (US) | 2013-09-11 | — | — | EP | claimed |
| WO-2012078270-A2 | EFFICIENT AND EFFECTIVE SUPPLEMENT SCREENING FOR THE DEVELOPMENT OF CHEMICALLY DEFINED MEDIA IN CELL CULTURE | ABBOTT LABORATORIES (ES) | 2012-06-14 | — | — | WO | claimed |
| US-20120129727-A1 | EFFICIENT AND EFFECTIVE SUPPLEMENT SCREENING FOR THE DEVELOPMENT OF CHEMICALLY DEFINED MEDIA IN CELL CULTURE | ABBOTT LABORATORIES (US) | 2012-05-24 | — | — | US | claimed |
| US-9068970-B2 | Efficient and effective supplement screening for the development of chemically defined media in cell culture | ABBVIE INC. (US) | 2015-06-30 | — | — | US | disclosed |
| EP-2635905-A2 | EFFICIENT AND EFFECTIVE SUPPLEMENT SCREENING FOR THE DEVELOPMENT OF CHEMICALLY DEFINED MEDIA IN CELL CULTURE | AbbVie Inc. (US) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012078270-A2 | EFFICIENT AND EFFECTIVE SUPPLEMENT SCREENING FOR THE DEVELOPMENT OF CHEMICALLY DEFINED MEDIA IN CELL CULTURE | ABBOTT LABORATORIES (ES) | 2012-06-14 | — | — | WO | disclosed |
| US-20120129727-A1 | EFFICIENT AND EFFECTIVE SUPPLEMENT SCREENING FOR THE DEVELOPMENT OF CHEMICALLY DEFINED MEDIA IN CELL CULTURE | ABBOTT LABORATORIES (US) | 2012-05-24 | — | — | US | disclosed |
| EP-2427773-A1 | METHOD OF DIAGNOSING ASPHYXIA | Keller, Matthias (DE) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128054-A1 | METHOD OF DIAGNOSING ASPHYXIA | BIOCRATES LIFE SCIENCES AG (AT) | 2010-11-11 | — | — | WO | disclosed |
| WO-1998013037-A1 | METHODS OF USING AGMATINE TO REDUCE INTRACELLULAR POLYAMINE LEVELS AND TO INHIBIT INDUCIBLE NITRIC OXIDE SYNTHASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-04-02 | — | — | WO | disclosed |