Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 4/20 | 0.48 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 4/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 4/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15623136 | 0.80 | AKT1 (0.49) | HAO1ALDH1A1TRPV1 | |
| SCHEMBL15881011 | 0.77 | ALDH1A1 (0.51) | HAO1RARBALDH1A1MEN1RARA | |
| SCHEMBL24534804 | 0.77 | RARB (0.54) | HAO1RARBALDH1A1MEN1RARA | |
| SCHEMBL15623138 | 0.77 | S1PR1 (0.60) | THRATHRB | |
| SCHEMBL15623170 | 0.75 | AKT1 (0.52) | HAO1ALDH1A1TRPV1 | |
| SCHEMBL24534825 | 0.75 | PLK1 (0.56) | HAO1RARBALDH1A1MEN1RARA | |
| SCHEMBL15623135 | 0.75 | AKT1 (0.49) | HAO1ALDH1A1TRPV1 | |
| SCHEMBL8884118 | 0.73 | RARB (0.59) | HAO1RARBALDH1A1MEN1RARA | |
| SCHEMBL9215324 | 0.73 | RARB (0.59) | HAO1RARBALDH1A1MEN1RARA | |
| SCHEMBL9491031 | 0.73 | L3MBTL1 (0.71) | RARBALDH1A1MEN1RARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680282-B2 | Cyclic inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2014-03-25 | — | — | US | disclosed |