Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15623139 | 0.89 | TAAR1 (0.40) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL15623137 | 0.71 | HAO1 (0.49) | ALDH1A1MAPTTRPV1 | |
| SCHEMBL13761337 | 0.69 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL20722128 | 0.67 | MEN1 (0.38) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL15623140 | 0.67 | KDM4E (0.52) | ALDH1A1SMN1; SMN2MAPTKDM4ENPC1 | |
| SCHEMBL24401235 | 0.67 | TDP1 (0.60) | ALDH1A1MAPTNPC1L3MBTL1POLB | |
| SCHEMBL15623135 | 0.66 | AKT1 (0.49) | ALDH1A1SMN1; SMN2KDM4ETRPV1LMNA | |
| SCHEMBL14823026 | 0.65 | S1PR1 (0.46) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL12319261 | 0.65 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL13761382 | 0.64 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680282-B2 | Cyclic inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2014-03-25 | — | — | US | disclosed |