Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15623139 | 0.77 | TAAR1 (0.40) | KDM4EALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL14822984 | 0.72 | LMNA (0.54) | KDM4EALDH1A1LMNAL3MBTL1CHRNA4 | |
| SCHEMBL2109722 | 0.70 | ALDH1A1 (0.69) | KDM4EALDH1A1LMNAL3MBTL1CHRNA4 | |
| Hydrochloric Acid SCHEMBL3323816 | 0.68 | ALDH1A1 (0.67) | KDM4EALDH1A1LMNAL3MBTL1CHRNA4 | |
| SCHEMBL15623160 | 0.68 | KDM4E (0.49) | KDM4EALDH1A1LMNAL3MBTL1CHRNA4 | |
| SCHEMBL13409928 | 0.67 | ALDH1A1 (0.51) | KDM4EALDH1A1LMNAL3MBTL1CHRNA4 | |
| SCHEMBL3323814 | 0.67 | KDM4E (0.65) | KDM4EALDH1A1LMNAL3MBTL1CHRNA4 | |
| SCHEMBL15623159 | 0.67 | ALDH1A1 (0.40) | KDM4EALDH1A1LMNAL3MBTL1POLB | |
| Trifluoroacetic Acid SCHEMBL979997 | 0.66 | KDM4E (0.44) | KDM4EALDH1A1LMNAL3MBTL1CHRNA4 | |
| SCHEMBL12923308 | 0.65 | KDM4E (0.48) | KDM4EALDH1A1LMNAL3MBTL1CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680282-B2 | Cyclic inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2014-03-25 | — | — | US | disclosed |