Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.47 |
| ▸ | NPC1 | O15118 | 12/20 | 0.47 |
| ▸ | AR | P10275 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15625690 | 0.81 | RAB9A (0.44) | RAB9ANPC1ARCYP3A4CYP1A2 | |
| SCHEMBL15625693 | 0.79 | RAB9A (0.42) | RAB9ANPC1ARCYP3A4CYP1A2 | |
| SCHEMBL15625703 | 0.76 | NPC1 (0.44) | RAB9ANPC1ARCYP3A4CYP1A2 | |
| SCHEMBL15625692 | 0.74 | NPC1 (0.49) | RAB9ANPC1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL15625698 | 0.74 | NPC1 (0.49) | RAB9ANPC1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL34467584 | 0.72 | NPC1 (0.63) | RAB9ANPC1ARCYP3A4CYP1A2 | |
| SCHEMBL240431 | 0.72 | NPC1 (0.63) | RAB9ANPC1ARCYP3A4CYP1A2 | |
| SCHEMBL15625709 | 0.72 | CNR1 (0.41) | RAB9ANPC1ARCYP3A4CYP1A2 | |
| SCHEMBL12075034 | 0.71 | TERT (0.43) | RAB9AKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL12112870 | 0.71 | RAB9A (0.80) | RAB9ANPC1ARCYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140088144-A1 | INHIBITING MICROBIAL INFECTIONS | THE UNIVERSITY OF KANSAS (US) | 2014-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088144-A1 | INHIBITING MICROBIAL INFECTIONS | ARAF, VGF, LITAF | RAB9A 1405/4885NPC1 4589/4885AR 1972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.