Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLI1 | P08151 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16399741 | 1.00 | GLI1 (0.36) | GLI1EPHX1CYP2D6KDM4EMAPT | |
| Acetic Acid SCHEMBL17686041 | 0.94 | EPHX1 (0.33) | GLI1EPHX1CYP2D6CYP1A2ALOX15 | |
| SCHEMBL7885822 | 0.80 | CYP2D6 (0.45) | CYP2D6KDM4EKMT2ACYP1A2ALOX15 | |
| SCHEMBL5872389 | 0.80 | — | — | |
| SCHEMBL8691197 | 0.80 | CYP2D6 (0.45) | CYP2D6KDM4EKMT2ACYP1A2ALOX15 | |
| SCHEMBL12860960 | 0.80 | — | — | |
| SCHEMBL8248640 | 0.80 | — | — | |
| SCHEMBL16921041 | 0.80 | — | — | |
| SCHEMBL8255222 | 0.80 | — | — | |
| SCHEMBL14290005 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9359353-B2 | Nitrogen containing compounds and their use | WOCKHARDT LIMITED (IN) | 2016-06-07 | — | — | US | disclosed |
| US-20150322067-A1 | NITROGEN CONTAINING COMPOUNDS AND THEIR USE | WOCKHARDT LIMITED (IN) | 2015-11-12 | — | — | US | disclosed |
| US-9115131-B2 | Nitrogen containing compounds and their use | WOCKHARDT LTD. (IN) | 2015-08-25 | — | — | US | disclosed |
| US-9090616-B2 | Nitrogen containing compounds and their use | WOCKHARDT LTD. (IN) | 2015-07-28 | — | — | US | disclosed |
| US-20150166537-A1 | NITROGEN CONTAINING COMPOUNDS AND THEIR USE | WOCKHARDT LTD. (IN) | 2015-06-18 | — | — | US | disclosed |
| US-20150141394-A1 | NITROGEN CONTAINING COMPOUNDS AND THEIR USE | WOCKHARDT LTD. (IN) | 2015-05-21 | — | — | US | disclosed |
| US-8969334-B2 | Nitrogen containing compounds and their use | WOCKHARDT LTD. (IN) | 2015-03-03 | — | — | US | disclosed |
| US-8969567-B2 | Nitrogen containing compounds and their use | WOCKHARDT LTD. (IN) | 2015-03-03 | — | — | US | disclosed |
| US-20140296526-A1 | NITROGEN CONTAINING COMPOUNDS AND THEIR USE | WOCKHARDT LIMITED (IN) | 2014-10-02 | — | — | US | disclosed |
| US-8754102-B2 | Nitrogen containing compounds and their use | WOCKHARDT LTD. (IN) | 2014-06-17 | — | — | US | disclosed |
| US-20140088070-A1 | NITROGEN CONTAINING COMPOUNDS AND THEIR USE | WOCKHARDT LIMITED (IN) | 2014-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296526-A1 | NITROGEN CONTAINING COMPOUNDS AND THEIR USE | NOS2, NOS1, NOS3 | GLI1 2204/4885EPHX1 1883/4885CYP2D6 448/4885 |
| US-20150166537-A1 | NITROGEN CONTAINING COMPOUNDS AND THEIR USE | NOS2, NOS1, NOS3 | GLI1 2204/4885EPHX1 1883/4885CYP2D6 448/4885 |
| US-20150141394-A1 | NITROGEN CONTAINING COMPOUNDS AND THEIR USE | NOS2, NOS1, NOS3 | GLI1 2204/4885EPHX1 1883/4885CYP2D6 448/4885 |
| US-20150322067-A1 | NITROGEN CONTAINING COMPOUNDS AND THEIR USE | NOS2, NOS1, NOS3 | GLI1 2204/4885EPHX1 1883/4885CYP2D6 448/4885 |
| US-20140088070-A1 | NITROGEN CONTAINING COMPOUNDS AND THEIR USE | NOS2, NOS1, NOS3 | GLI1 2204/4885EPHX1 1883/4885CYP2D6 448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.